Estimation of Serum Calcium and Vitamin D Levels in Patients with Benign Paroxysmal Positional Vertigo | ||
| International Journal of Medical Arts | ||
| Articles in Press, Accepted Manuscript, Available Online from 14 November 2025 | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ijma.2025.407060.2223 | ||
| Authors | ||
| Yossuf Mohamed Reda* 1; Elshahat Ibrahim Ismail Elshokry2; Mahmoud Farag Mohamed Salem3; mohamed hussein abdelazim4 | ||
| 1Department of Otorhinolaryngology, Damietta Faculty of Medicine, Al-Azhar University, Damietta, Egypt | ||
| 2Department of Audiovestibular Medicine,Faculty of Medicine Mansoura University, Mansoura, Egypt | ||
| 3Deparmtent of Clinical Pathology, Damietta Faculty of Medicine, Al-Azhar University, Damietta, Egypt | ||
| 4lecturer of otorhinolaryngolgy,al azhar faculty of medicine new dameitta | ||
| Abstract | ||
| Background: Benign paroxysmal positional vertigo (BPPV) is the most common cause of peripheral vertigo. Calcium homeostasis and vitamin D metabolism may play roles in its pathophysiology. BPPV is associated with the homeostasis of calcium. Aim and objectives: The purpose of this study was to estimate the blood levels of vitamin D and calcium in BPPV patients and investigate the relationship between them. Patients and methods: This cross-sectional controlled study included 80 subjects attending at otorhinolaryngology department, Al-Azhar University Hospital in Damietta.The patients will be divided into 2 groups, group 1 that will include 40 patients diagnosed with BPPV, and group 2 that will include 40 healthy individuals Results: No statistically significant differences were found between the BPPV and control groups in serum calcium or vitamin D levels. However, a significant negative correlation was observed between the frequency of BPPV episodes and vitamin D levels (r = -0.375). The most common BPPV type was posterior semicircular canal (70%). Conclusion: The current study's findings demonstrated that the study population's blood vitamin D levels were typically low. There was no association found between BPPV and blood calcium and vitamin D levels. This might be as a result of the general population in this region having generally lower blood levels of vitamin D. However, a statistically significant negative association was found between blood vitamin D levels and the number of BPPV episodes, indicating that the likelihood of BPPV recurrence increases as vitamin D levels fall. | ||
| Keywords | ||
| Benign paroxysmal positional vertigo; Canalolithiasis; Cupulolithiasis | ||
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