Characteristics of acute methanol poisoned patients admitted to Mansoura Emergency Hospital:Retrospective cross-sectional study | ||
| Mansoura Journal of Forensic Medicine and Clinical Toxicology | ||
| Articles in Press, Accepted Manuscript, Available Online from 14 November 2025 | ||
| Document Type: Original Article | ||
| DOI: 10.21608/mjfmct.2025.419929.1102 | ||
| Author | ||
| osama aly shabka* | ||
| mansoura | ||
| Abstract | ||
| Toxicity by methanol is attributed to its metabolites, which are responsible for CNS depression, optic neuropathy, and metabolic acidosis. This is a study aimed at analyzing demographic data, diagnostic and therapeutic characteristics, and complications of patients admitted to Mansoura Emergency Hospital because of acute methanol poisoning. This is a retrospective cohort study spanning a 5-year period, conducted at Mansoura Emergency Hospital. Out of 60 patients included in the study, 40 patients were discharged without complications (Group I, 66.6%). Sixteen patients were discharged with complications (group II, 26.6%). 4 patients died (group III, 6.6%). The main complaint was vomiting and abdominal colic, followed by impairment of vision and neurological manifestations. Poor outcome was associated with delayed hospital admission, decreased arterial pH, serum bicarbonate, the mean GCS, and increased need for ventilation, RBS, serum creatinine, SGOT, and SGPT. Out of 16 patients who were discharged with complications, two patients had a visual field defect and became unfortunately blind 3 months after discharge. It is concluded that risk factors of poor outcome include delayed hospital admission, metabolic acidosis, need for ventilation, visual field defect, and low GCS. It is recommended not to allow methanol-poisoned patients with visual field defects to be discharged; instead, close observation and care by both a toxicologist and ophthalmologist is mandatory. Keywords: methanol, clinical, laboratory, recommendations | ||
| Keywords | ||
| demographic; clinical; laboratory; mortality; recommendations | ||
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