Comparative Toxicity, Interspecific Susceptibility, and Enzyme Activity Responses to First- to Fourth-Generation Neonicotinoid Insecticides in Aphis gossypii Glover and Myzus persicae Sulzer under Laboratory Conditions | ||
| Journal of Plant Protection and Pathology | ||
| Articles in Press, Accepted Manuscript, Available Online from 16 November 2025 PDF (567.16 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/jppp.2025.434862.1393 | ||
| Authors | ||
| B. S. M. Soliman; M. M. R. Attia; A. A. E. Darwish* ; Awatef S. Mansy | ||
| Plant protection department, Faculty of Agriculture, Damanhour University, Egypt | ||
| Abstract | ||
| This study evaluated the toxicity of six neonicotinoid insecticides from four chemical generations against Aphis gossypii and Myzus persicae under laboratory conditions after 24 and 48 hours of exposure. Sulfoxaflor, representing the fourth generation, consistently showed the highest toxicity against both aphid species, with the lowest LC50 values and a toxicity index of 100. Second-generation insecticides (clothianidin and thiamethoxam) exhibited moderate to high efficacy, whereas first-generation (imidacloprid and acetamiprid) and third-generation (dinotefuran) compounds showed lower toxic effects. Time-dependent increases in toxicity were observed for most insecticides. Comparative analysis revealed interspecific differences: M. persicae exhibited greater tolerance to most compounds than A. gossypii, suggesting species-specific resistance profiles. Biochemical assays indicated that several neonicotinoids significantly increased acetylcholinesterase (AChE) and glutathione S-transferase (GST) activity in M. persicae, implying adaptive detoxification mechanisms. In contrast, sulfoxaflor significantly inhibited AChE activity, highlighting its distinct neurotoxic mode of action. These findings underscore the importance of chemical innovation and resistance management in aphid control programs. Sulfoxaflor emerged as the most promising candidate due to its high efficacy and novel mechanism, making it suitable for integrated pest management (IPM). However, rotating insecticides and monitoring susceptibility remain essential to delay resistance development. | ||
| Keywords | ||
| Aphis gossypii; Myzus persicae; neonicotinoids; toxicity; AchE; GST | ||
|
Statistics Article View: 4 |
||
