Assessing Right Atrial Function With 2D Speckle Tracking Echocardiography in Inferior ST-Elevation Myocardial Infarction Patients Undergoing Primary Percutaneous Coronary Intervention | ||
| Ain Shams Medical Journal | ||
| Articles in Press, Accepted Manuscript, Available Online from 19 November 2025 PDF (362.63 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/asmj.2025.370459.1420 | ||
| Authors | ||
| Khalid Karem* ; Mikhail M Zareef; Ahmed El Missiri; Ahmed Onsy | ||
| Cardiology Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt. | ||
| Abstract | ||
| Background: Right atrium (RA) plays a crucial role in cardiac function, yet evaluation of RA function in myocardial infarction (MI) has been underexplored. Inferior ST segment myocardial infarction (STEMI) may affect RA function. Two-dimensional speckle tracking echocardiography (2D-STE) provides a novel, non-invasive means of assessing RA mechanics. Aim: To evaluate and compare RA function in patients with inferior STEMI, with and without RV infarction, against healthy controls using 2D-STE. Patients and Methods: This prospective, observational, case-control study included 150 participants: 100 patients with inferior STEMI undergoing primary percutaneous coronary intervention (PCI) and 50 age-matched healthy controls. STEMI group was further divided into those with RV infarction (n = 26) and those without (n = 74). RA function was assessed using 2D-STE, with RA strain parameters measured in reservoir (RASr), conduit (RAScd), and contraction (RASct) phases. Results: Compared to controls, patients with inferior STEMI exhibited significantly reduced RASr (33.54 ± 5.98% vs. 42.42 ± 5.85%, p < 0.001) and RAScd (22.48 ± 5.16% vs. 25.92 ± 4.21%, p < 0.001), while RASct remained comparable (p = 0.062). Within the STEMI group, RA strain parameters did not significantly differ between those with and without RV infarction (p > 0.05). However, RA emptying fraction (RAEF) was significantly lower in RV infarction patients (56.12 ± 10.58% vs. 60.26 ± 7.18%, p = 0.029). Conclusion: RA reservoir and conduit functions are significantly impaired in inferior STEMI patients, irrespective of RV infarction. However, RAEF is reduced in patients with RV infarction, correlating with impaired RV function. | ||
| Keywords | ||
| Inferior STEMI; myocardial infarction; right atrium; right ventricular infarction; speckle tracking echocardiography | ||
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