Predictors of Early Variceal Rebleeding after Endoscopic Therapy in Cirrhotic Patients | ||
| Ain Shams Medical Journal | ||
| Articles in Press, Accepted Manuscript, Available Online from 19 November 2025 PDF (495.54 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/asmj.2025.371942.1425 | ||
| Authors | ||
| Mennat-Allah Mohamed El Sawaf* 1; Madonna Magdy Fahmy2; Saber Abd Elrahman Ismail2; Sahar Abdel Tawab EL Yamani2; Lobna Ahmed Abo Ali2; Boshra Elsayed Talha2 | ||
| 1Tropical medicine and infectious disease Department , Faculty of Medicine, Tanta University, Tanta, Egypt. | ||
| 2Tropical Medicine and Infectious Disease Department, Faculty of Medicine, Tanta University, Tanta, Egypt. | ||
| Abstract | ||
| Background: The management of cirrhotic patients experiencing variceal bleeding focuses on controlling the hemorrhage and preventing early rebleeding and mortality. Local risk factors, such as an HVPG above 12 mmHg, the size of the varices, and the presence of warning signs during endoscopy, are key predictors for early variceal rebleeding. Aim: The work aimed predict risk factors for early variceal rebleeding after endoscopic therapy. Methods: In this prospective study, 184 patients were enrolled from the endoscopy unit at Tanta University Hospital's Tropical Medicine and Infectious Diseases Department in Egypt. The study's duration was 5 months, encompassing both recruitment and follow-up. Results: The results of the multivariate logistic regression analysis indicated that a Child-Pugh score of ≥10, MELD score ≥16, presence of fundal varices, serum creatinine and INR were independent predictors for 5-days rebleeding. Conclusions: Child-Pugh score, MELD score, serum creatinine, INR and fundal varices are independent risk factors for 5-day rebleeding. | ||
| Keywords | ||
| Cirrhotic patients; endoscopic therapy; esophageal varices; variceal rebleeding | ||
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