Anxiety and Depressive Symptoms in Juvenile Idiopathic Arthritis Using PROMIS Measures | ||
| Benha Medical Journal | ||
| Articles in Press, Accepted Manuscript, Available Online from 20 November 2025 PDF (629.42 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/bmfj.2025.392343.2460 | ||
| Authors | ||
| Ahmed A. El-Sharkawy1; Enas M. Nor El-Deen2; Asmaa s. Mohamed3; Eman S. Ali* 4 | ||
| 1Professor of Pediatrics and Neonatology Faculty of Medicine – Benha University | ||
| 2Lecturer of Pediatrics and Neonatology Faculty of Medicine – Benha University | ||
| 3Lecturer of psychiatry Faculty of medicine – Benha University | ||
| 4M.B.B.Ch, Faculty of Medicine, Benha University | ||
| Abstract | ||
| Background and Aim: Juvenile idiopathic arthritis (JIA) and other chronic inflammatory diseases are associated with decreased quality of life and mental health issues. This study aimed to use PROMIS measures to assess two things: (1) how children with JIA and healthy controls exhibited anxiety and depressive symptoms, and (2) how these symptoms were related to the severity and length of the disease. Methods: In this cross-sectional study, 50 children with JIA (mean age 10.95 ± 3.9 years; 62% female) and 50 age-/sex-matched controls were evaluated. Assessments included clinical joint examination, PROMIS Pediatric Short Forms (Anxiety/Depression), Childhood Health Assessment Questionnaire (CHAQ), and cJADAS10. Results: The JIA group had significantly higher mean T-scores for anxiety (60.45 ± 6 vs. 41.96 ± 7.46) and depression (61.41 ± 9 vs. 46.54 ± 5.66) than controls (p < 0.001). Notably, 68% of JIA patients had moderate anxiety, and 44% had moderate-to-severe depression. Longer disease duration correlated with worse anxiety (p = 0.001) and depression (p = 0.007), but no significant association was found with cJADAS10 activity. Functional impairments (CHAQ) were linked to higher depression scores (p < 0.01). Conclusion: Children with JIA exhibit significantly greater anxiety and depressive symptoms than healthy peers, particularly those with prolonged disease duration or mobility limitations. PROMIS measures are valuable tools for standardized mental health screening in JIA. | ||
| Keywords | ||
| Juvenile Idiopathic Arthritis; JIA; Anxiety; Depression; PROMIS | ||
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