Neonates with sepsis and cardiovascular dysfunction
EL. Khayat, W., Mustafa, M., Abdel Rahman, E., Abdel Haie, O., Goda, E. (2025). Neonates with sepsis and cardiovascular dysfunction. EKB Journal Management System, (), -. doi: 10.21608/bmfj.2025.415316.2623
Walaa A. EL. Khayat; Mustafa A. Mustafa; Eman G. Abdel Rahman; Omaima M. Abdel Haie; Eman k. Goda. "Neonates with sepsis and cardiovascular dysfunction". EKB Journal Management System, , , 2025, -. doi: 10.21608/bmfj.2025.415316.2623
EL. Khayat, W., Mustafa, M., Abdel Rahman, E., Abdel Haie, O., Goda, E. (2025). 'Neonates with sepsis and cardiovascular dysfunction', EKB Journal Management System, (), pp. -. doi: 10.21608/bmfj.2025.415316.2623
EL. Khayat, W., Mustafa, M., Abdel Rahman, E., Abdel Haie, O., Goda, E. Neonates with sepsis and cardiovascular dysfunction. EKB Journal Management System, 2025; (): -. doi: 10.21608/bmfj.2025.415316.2623

Neonates with sepsis and cardiovascular dysfunction

Benha Medical Journal
Articles in Press, Accepted Manuscript, Available Online from 20 November 2025    PDF (581.56 K)
Document Type: Original Article
DOI: 10.21608/bmfj.2025.415316.2623
Authors
Walaa A. EL. Khayat* 1; Mustafa A. Mustafa2; Eman G. Abdel Rahman3; Omaima M. Abdel Haie4; Eman k. Goda5
1Msc. Pediatric, faculty of medicine Benha University
2Professor of Pediatrics Faculty of Medicine - Benha University
3Assistant Professor of pediatrics Faculty of Medicine - Benha University
4Professor of pediatrics Faculty of Medicine- Benha University
5Lecturer of pediatrics Faculty of Medicine- Benha University
Abstract
Background: Neonatal sepsis (NS) is a common cause of morbidity and mortality in newborns. Cardiovascular dysfunction (CVD), including biventricular impairment, altered vascular tone, and elevated pulmonary arterial pressure (PAP), is a frequent complication. Aim: To evaluate CVD in neonates with NS admitted to the NICU at Benha University Hospital. Subjects and Methods: This prospective observational research included neonates with NS in the NICU between July 2024 and December 2024, alongside an age- and sex-matched control group. All participants underwent functional echocardiography (f-Echo) for cardiac assessment. Results: In both NS and control groups, 50% were male. Birth weight ranged from 2.2–3.5 kg (mean 2.9 ± 0.3 kg). Thrombocytopenia was observed in 63.3% of NS cases, leukocytosis in 16.7%, and 36.7% exhibited significant neutrophil shift. Echocardiography demonstrated notable CVD in NS patients, which improved significantly following sepsis resolution. Conclusion: NS is associated with marked CVD, detectable and monitorable via f-Echo, highlighting the importance of cardiac evaluation in septic neonates.
Keywords
Neonatal sepsis; Targeted neonatal echocardiography; Myocardial dysfunction; inflammatory response syndrome
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