Prevalence and Risk Factors of Metabolic Associated Fatty Liver Disease in Benha University Hospitals Employees, Egypt: A Cross-Sectional Study.
Mohamady, M., El Sayed, M., El Badawy, A., El Sayed, A., Ibrahem, W., Abdelmoniem, R. (2025). Prevalence and Risk Factors of Metabolic Associated Fatty Liver Disease in Benha University Hospitals Employees, Egypt: A Cross-Sectional Study.. EKB Journal Management System, (), -. doi: 10.21608/bmfj.2025.412427.2606
Marwa S. Mohamady; Mohamed S. El Sayed; Ayman M. El Badawy; Amira M. El Sayed; Walaa M. Ibrahem; Rasha O. Abdelmoniem. "Prevalence and Risk Factors of Metabolic Associated Fatty Liver Disease in Benha University Hospitals Employees, Egypt: A Cross-Sectional Study.". EKB Journal Management System, , , 2025, -. doi: 10.21608/bmfj.2025.412427.2606
Mohamady, M., El Sayed, M., El Badawy, A., El Sayed, A., Ibrahem, W., Abdelmoniem, R. (2025). 'Prevalence and Risk Factors of Metabolic Associated Fatty Liver Disease in Benha University Hospitals Employees, Egypt: A Cross-Sectional Study.', EKB Journal Management System, (), pp. -. doi: 10.21608/bmfj.2025.412427.2606
Mohamady, M., El Sayed, M., El Badawy, A., El Sayed, A., Ibrahem, W., Abdelmoniem, R. Prevalence and Risk Factors of Metabolic Associated Fatty Liver Disease in Benha University Hospitals Employees, Egypt: A Cross-Sectional Study.. EKB Journal Management System, 2025; (): -. doi: 10.21608/bmfj.2025.412427.2606

Prevalence and Risk Factors of Metabolic Associated Fatty Liver Disease in Benha University Hospitals Employees, Egypt: A Cross-Sectional Study.

Benha Medical Journal
Articles in Press, Accepted Manuscript, Available Online from 22 November 2025    PDF (1.01 M)
Document Type: Original Article
DOI: 10.21608/bmfj.2025.412427.2606
Authors
Marwa S. Mohamady* 1; Mohamed S. El Sayed2; Ayman M. El Badawy2; Amira M. El Sayed3; Walaa M. Ibrahem4; Rasha O. Abdelmoniem3
1Internal Medicine, Faculty of Medicine, Benha University, Benha, Egypt
2Professor of Internal Medicine, Faculty of Medicine, Benha University, Benha, Egypt
3Assistant Professor of Internal Medicine, Faculty of Medicine, Benha University, Benha, Egypt
4Lecturer of Internal Medicine, Faculty of Medicine, Benha University, Benha, Egypt
Abstract
Background: MAFLD is a common liver disorder linked to metabolic dysfunction and poses a growing public health challenge. This study aims to determine the prevalence and associated risk factors of MAFLD among employees at Benha University Hospitals, Egypt. Methods: A cross-sectional study was conducted involving 85 adult hospital employees over the period from July 2022 to July 2023. Results: MAFLD was identified in 71.8% of participants. The MAFLD group had significantly higher age (42 ± 9 vs. 37 ± 8 years, P = 0.032), BMI (35.2 ± 5.4 vs. 30.3 ± 6.3 kg/m², P < 0.001), FLI (82 ± 13 vs. 56 ± 33, P < 0.001), and serum ferritin (315 vs. 195 ng/mL, P < 0.001). ROC analysis showed good predictive performance for serum ferritin (AUC = 0.760) and BMI (AUC = 0.745). Logistic regression identified FLI (OR = 1.102, P = 0.002) and serum ferritin (OR = 1.116, P = 0.007) as independent predictors of MAFLD, while BMI and TGs showed borderline significance. Conclusion: MAFLD is highly prevalent among hospital employees and is strongly related with metabolic risk factors. FLI and serum ferritin are reliable non-invasive predictors. Targeted screening and metabolic control strategies are essential to address this growing burden.
Keywords
Fatty Liver Index; Metabolic Associated Fatty Liver Disease; Serum Ferritin; Metabolic Syndrome; Hepatic Steatosis
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