Evaluation of Parenteral Antioxidant as a Protective Therapy Against Electromagnetic Radiation Produced by Cell Phones on Hematological and Biochemical Parameters in Rats | ||
| Journal of Advanced Pharmacy Research | ||
| Article 3, Volume 2, Issue 1, January 2018, Pages 28-35 PDF (737.01 K) | ||
| Document Type: Research Article | ||
| DOI: 10.21608/aprh.2017.4833 | ||
| Authors | ||
| Samia Omar* ; Mohamed Nasr; Diana A. Rafla | ||
| Department of Pharmaceutics, Faculty of Pharmacy, Helwan University, Ain Helwan, Cairo11795, Egypt | ||
| Abstract | ||
| Objectives: Radiofrequency of mobile phones may affect biological systems by increasing free radicals and by changing the antioxidant defense systems of tissues, thus leading to oxidative stress. L-cysteine, as a glutathione precursor, has an antioxidant property that may prevent oxidative damage to normal cellular processes. Methods: The effect of different concentrations of parentral L-CyS-HCl against harmful effects of EMR on rats' blood was studied namely: hematological parameters (osmotic fragility and blood picture), and biochemical parameters (reduced glutathione and malondialdehyde levels). Results: The results revealed that 20 mg parenteral L-CyS-HCl showed high protection for EMR radiated rats against hemolysis. In addition, EMR radiated rats received 20 mg parenteral L-CyS-HCl showed normal blood picture, GSH and Malondialdehyde levels, compared to radiated untreated rats. Conclusion:Parenteral L-CyS-HCl can be used for protection against mobile phone hazards | ||
| Keywords | ||
| electromagnetic radiation (EMR); Glutathione (GSH; Mobile phone hazards; L-cysteine; Oxidative Stress | ||
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