IMMUNE HABITUAL ABORTION: INCIDENCE AND MANAGEMENT | ||
| The Egyptian Journal of Fertility and Sterility | ||
| Article 6, Volume 9, 1,2, January 2005, Pages 39-42 PDF (258.57 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/egyfs.2005.5003 | ||
| Authors | ||
| Mohamed El Samra; Mohamed El Abd; Sherif Agag | ||
| Department of Obstetrics & Gynecology, Alexandria University, Egypt | ||
| Abstract | ||
| The objective of this study of patients with habitual abortion, was planned to determine their autoimmune profile and to try to prevent new abortions using low-dose aspirin (Rivo® 75mg) for 7 months with solupred® 20 mg in the first trimester only, or with low-dose aspirin alone. A total of 100 patients with three or more HA were investigated for antiphospholipid antibodies, antinuclear and anti thyroid antibodies. Among these patients, auto antibodies were present in 34% of the patients, in 82.4% of them anticardiolipin antibodies were found to be isolated alone or associated with lupus anticoagulant, anti thyroid, or, antinuclear antibodies. In auto antibodies-negative pregnant women treated by solupred and aspirin or aspirin alone, the success rate of live births was 90.9% (30 out of 33) and 75.7% (25 out of 33) rcspectivley (p < 0.01) in auto antibodies - positive patients treated with solupred and aspirin the success rate was 85.2% (29 out of 34) (not significant) solupred and aspirin seemed to he as efficient in auto antibodies - negative or positive women but better than aspirin alone in autoantibody - negative women. | ||
| Keywords | ||
| missed | ||
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