Inhibition of Human Breast cancer cells proliferation by Graviola crude extract | ||
| Recent Research in Genetics and Genomics | ||
| Article 1, Volume 1, Issue 1, 2019, Pages 1-7 PDF (754.27 K) | ||
| Document Type: Original Research Articles | ||
| DOI: 10.21608/rrgg.2019.50222 | ||
| Authors | ||
| Razan M.H Mohammed; Magda M. Noshy; Hanan R.H Mohamed* | ||
| Zoology Department; Faculty of science Cairo University; Giza, Egypt | ||
| Abstract | ||
| Rapid increases in cancer and human death cases, as well as the fatal side effects of chemotherapy, have forced the seek new safer anti-cancer drugs. Therefore, the current study was conducted to study the effect of Graviola leaf extract on the proliferation of human breast cancer (MCF-7) cell lines. MCF-7 cells were cultured and a Neutral red uptake assay was done to estimate the effect of Graviola extract on MCF-7 cells'''' proliferation. Treatment with different concentrations of Graviola leaf extract inhibited the proliferation of MCF-7 cells in a concentration-dependent manner. Conclusion: Graviola leaf extract has a promising inhibitory effect against the proliferation of MCF-7 cells. | ||
| Keywords | ||
| MCF-7 cells; Graviola; NR assay; proliferation; Cytotoxicity | ||
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