Neurological Study of Patients with Systemic Lupus Erythematosus | ||
| The Medical Journal of Cairo University | ||
| Article 34, Volume 87, March, March 2019, Pages 239-247 PDF (725.66 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/mjcu.2019.52346 | ||
| Authors | ||
| SAMAR F. MARZOUK, M.Sc.; ABEER A. SHAHBA, M.D.; MHAMED O. RABIE, M.D.; EL-SAYED A. TAG ELDIN, M.D. | ||
| The Departments of Neuropsychiatry* and Internal Medicine**, Faculty of Medicine, Tanta University | ||
| Abstract | ||
| Abstract Background: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease of unknown etiology affecting multiple organ systems including the joints, skin, heart, lungs, kidneys and the nervous system. Aim of Work: Is to study the neurological manifestations in patients with systemic lupus erythematosus attending Tanta University Hospitals over 6 months. Patients and Methods: Cross sectional study was carried out on 60 patients with SLE diagnosed according to American College of Rheumatology criteria attending Tanta University Hospitals during six months. Results: Mean age was 46.7±12.1. Fifty two patients were females and 8 patients were males. This study found that 43 patients showed neurological manifestations, headache was the most common representing 51.7% followed by cognitive impairment 46.7% and cerebrovascular stroke 13%. 6 patients complicated by seizures in whom 3 patients were focal. Focal slowing was the most common EEG abnormalities while white matter hyper intensity lesions were the most common MRI brain abnormalities. Conclusion: Neurological manifestations are frequent in SLE patients. Headache is the most common neurological manifestation followed by cognitive impairment. | ||
| Keywords | ||
| SLE, Neurological manifestations; headache | ||
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