Computed Tomography Versus Magnetic Resonance Imaging in Assessment of Recto-Sigmoid Cancer Local Recurrence in Patients with Elevated Carcinoembryonic Antigen | ||
| Zagazig University Medical Journal | ||
| Article 252, Volume 27, Issue 4, July 2021, Pages 724-734 PDF (776.46 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/zumj.2019.14444.1309 | ||
| Authors | ||
| Hend Abd Elmageed Mohsenah* 1; El Sayed Zidan2; Ahmed Al Smmak2; Ranya Almola2 | ||
| 1Radiodiagnosis department, Mit-Ghamr Oncology Center, Ministry of Health,Egypt | ||
| 2Radiodiagnosis department, Faculty of medicine, Zagazig university | ||
| Abstract | ||
| Background: Colorectal cancer is widely distributed. It is considered the third most common cancer worldwide. Despite performing potentially curative operations 25% to 40% develop tumor recurrence. The optimal strategy to detect recurrences at the earliest stage remains controverse. The aim of this study is to assess recto-sigmoid cancer local recurrence in patients with elevated CEA by contrast enhanced CT and contrast enhanced MRI and compare between both modalities. Methods: This study was carried out on 24 patients who underwent surgical excision of primary recto-sigmoid cancer and under post-operative follow up with elevated CEA level. CT and MRI were done, and the results were compared. Results: Our study included 24 their age's ranged from 23-76 years with the mean age 53 years. Twenty cases (83%) were confirmed to have recurrence while 4 cases elevated CEA levels were considered false positive. CT accuracy (79%), sensitivity (100%) and specificity (55%). These results were not as high as those of MR imaging where MRI accuracy (96%), sensitivity (100%) and specificity (91%). By using chi square test, there was no significant difference between CT and MRI in detection and assessment of locally recurrent recto sigmoid cancer patients with P value 0.3843. Conclusion: MRI has higher specificity than CT in determining pelvic recurrence recto-sigmoid cancer in patients with elevated CEA level. It can differentiate recurrent masses from post-operative scar tissue and determine preciously the site and type of local recurrence. However, CT is mandatory in these patients as a screening modality and follow up. | ||
| Keywords | ||
| recto-sigmoid; CEA; Recurrence; CT; MRI | ||
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