In vitro Antimicrobial Activity Evaluation of Newly Synthesized Furochromone Schiff Base Complexes | ||
| Egyptian Journal of Chemistry | ||
| Article 7, Volume 61, Issue 2, March and April 2018, Pages 295-304 PDF (619.44 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejchem.2018.2222.1180 | ||
| Authors | ||
| Mohammed M Shakdofa* 1; Hanan Abdel Hady Mousa2; Ammar Ahmed Labib3; Amira Abd El-All4; Fatma Bassyouni5 | ||
| 1Department of Inorganic Chemistry, National Research Centre, El-Bohouth St., Dokki, Cairo, Egypt | ||
| 2Department of Inorganic Chemistry, National Research Centre, El-bohouth St., P.O. 12622, Dokki, Cairo, Egypt | ||
| 3Inorganic Chemistry Department, National Research Centre, El Behoos St., Dokki, Cairo, Egypt. | ||
| 4Department of Natural and Microbial Products, National Research Centre, El-bohouth St., P.O. 12622, Dokki, Cairo, Egypt | ||
| 5Department of Natural and Microbial Products, National Research Centre, El-bohouth St., P.O. 12622, Dokki, Cai-ro, Egypt | ||
| Abstract | ||
| A series of VOII, NiII, CuII, CoII, MnII, CdII and ZnII complexes of new Schiff base ligand resulting form 4-aminoantipyrine and Furobenzopyrone were prepared. The structure of newly synthesized compounds (1-8) was proven by studying their elemental analyses, spectral data (IR, NMR, UV-vis), molar conductivity and magnetic susceptibility. In addition the in vitro antimicrobial activi-ty of all compounds was examined. The results cleared that nickel and zinc complexes exhibited promising activity compared with standard drug (chloramphenicol). | ||
| Keywords | ||
| Schiff base; Metal complexes; Antimicrobial; furochromone | ||
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