Association of Helicobacter Pylori Infection with Portal Hypertensive Gastropathy in Liver Cirrhosis | ||
| The Medical Journal of Cairo University | ||
| Article 25, Volume 86, June, June 2018, Pages 1281-1286 PDF (664.5 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/mjcu.2018.56293 | ||
| Authors | ||
| AFAF T. EL-NASHAR, M.D.; HASSAN A. HASSANIEN, M.D.; ASHRAF A. ASKER, M.D.; HANAA M. ABD EL-AZEEM, M.Sc. | ||
| The Departments of Pathology* and General Medicine**, Faculty of Medicine, Sohag University | ||
| Abstract | ||
| Abstract Background: Portal hypertensive gastropathy (PHG) is an important cause of morbidity in patients with Liver cirrhosis (LC). Helicobacter pylori (HP) infection is a common cause of gastritis and is an endemic disease in Egypt. Aim of the Work: To study the presence of H. pylori infection in cases of LC with and without PHG. Material and Methods: Fifty patients with LC including 25 cases with PHG and 25 cases without PHG who attended Sohag Faculty Hospital during the period 9/2016-3/2017 were examined for the presence of H pylori infection histologically using Hematoxyline and Eosin and Geimsa stains. The corre-lation between H pylori infection and the severity of PHG was studied statistically. Results: H. pylori were detected in 76% of cases of LC (72% in LC with PHG and 80% of cases LC without PHG). Although there was an association between H pylori infection and the severity of PHG (5/7 cases), there was no statistically significant difference between H pylori infection and PHG. Conclusion: H. pylori infection can be seen in cases of LC irrespective of the presence or absence of PHG more than in general population. | ||
| Keywords | ||
| H. pylori – PHG – Liver cirrhosis – Geimsa stain | ||
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