Estrogen receptor alpha XbaI polymorphism is associated with higher relaxin-3 levels in women with metabolic syndrome
Mehanna, E., Mesbah, N., Ghattas, M., Abo-Elmatty, D. (2017). Estrogen receptor alpha XbaI polymorphism is associated with higher relaxin-3 levels in women with metabolic syndrome. EKB Journal Management System, 1(1), 17-21. doi: 10.21608/rpbs.2018.5916
Eman T. Mehanna; Noha M. Mesbah; Maivel H. Ghattas; Dina M. Abo-Elmatty. "Estrogen receptor alpha XbaI polymorphism is associated with higher relaxin-3 levels in women with metabolic syndrome". EKB Journal Management System, 1, 1, 2017, 17-21. doi: 10.21608/rpbs.2018.5916
Mehanna, E., Mesbah, N., Ghattas, M., Abo-Elmatty, D. (2017). 'Estrogen receptor alpha XbaI polymorphism is associated with higher relaxin-3 levels in women with metabolic syndrome', EKB Journal Management System, 1(1), pp. 17-21. doi: 10.21608/rpbs.2018.5916
Mehanna, E., Mesbah, N., Ghattas, M., Abo-Elmatty, D. Estrogen receptor alpha XbaI polymorphism is associated with higher relaxin-3 levels in women with metabolic syndrome. EKB Journal Management System, 2017; 1(1): 17-21. doi: 10.21608/rpbs.2018.5916

Estrogen receptor alpha XbaI polymorphism is associated with higher relaxin-3 levels in women with metabolic syndrome

Records of Pharmaceutical and Biomedical Sciences
Article 3, Volume 1, Issue 1, March 2017, Page 17-21  XML PDF (643.62 K)
Document Type: Original Article
DOI: 10.21608/rpbs.2018.5916
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Authors
Eman T. Mehanna email orcid 1; Noha M. Mesbah1; Maivel H. Ghattas2; Dina M. Abo-Elmatty1
1Department of Biochemistry, Faculty of Pharmacy, Suez Canal University, Ismailia, 41522, Egypt
2Department of Medical Biochemistry, Faculty of Medicine, Port Said University, Port Said, 42526, Egypt
Abstract
Relaxin-3 is known to play a role in appetite regulation, increasing food intake and body weight. This study aimed to assess the relation of relaxin-3 with ERS1 XbaI and PvuII polymorphisms. One hundred female patients with metabolic syndrome were investigated. The genotypes of ESR1 XbaI and PvuII polymorphisms were assessed with PCR-RFLP. Serum relaxin-3 level was measured for all participants using ELISA. Higher relaxin-3 levels showed association with the minor GG genotype of ESR-1 XbaI polymorphism but not PvuII polymorphism.
Keywords
Plicosepalus acacia; Loranthaceae; antimicrobial activity
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