Diffusion-weighted Magnetic Resonance Imaging of Sinonasal Masses: Does Bone Erosion or Destruction Alter the Apparent Diffusion Coefficient Value in Differentiating Benign from Malignant Masses?
Osman, M., Soliman, R., Imam, H. (2015). Diffusion-weighted Magnetic Resonance Imaging of Sinonasal Masses: Does Bone Erosion or Destruction Alter the Apparent Diffusion Coefficient Value in Differentiating Benign from Malignant Masses?. EKB Journal Management System, 2(2), 33-40. doi: 10.21608/ejnso.2015.61544
M M Osman; R K Soliman; H M.K. Imam. "Diffusion-weighted Magnetic Resonance Imaging of Sinonasal Masses: Does Bone Erosion or Destruction Alter the Apparent Diffusion Coefficient Value in Differentiating Benign from Malignant Masses?". EKB Journal Management System, 2, 2, 2015, 33-40. doi: 10.21608/ejnso.2015.61544
Osman, M., Soliman, R., Imam, H. (2015). 'Diffusion-weighted Magnetic Resonance Imaging of Sinonasal Masses: Does Bone Erosion or Destruction Alter the Apparent Diffusion Coefficient Value in Differentiating Benign from Malignant Masses?', EKB Journal Management System, 2(2), pp. 33-40. doi: 10.21608/ejnso.2015.61544
Osman, M., Soliman, R., Imam, H. Diffusion-weighted Magnetic Resonance Imaging of Sinonasal Masses: Does Bone Erosion or Destruction Alter the Apparent Diffusion Coefficient Value in Differentiating Benign from Malignant Masses?. EKB Journal Management System, 2015; 2(2): 33-40. doi: 10.21608/ejnso.2015.61544

Diffusion-weighted Magnetic Resonance Imaging of Sinonasal Masses: Does Bone Erosion or Destruction Alter the Apparent Diffusion Coefficient Value in Differentiating Benign from Malignant Masses?

Egyptian Journal of Neck Surgery and Otorhinolaryngology
Article 2, Volume 2, Issue 2, June 2015, Page 33-40  XML PDF (325.66 K)
DOI: 10.21608/ejnso.2015.61544
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Authors
M M Osman; R K Soliman; H M.K. Imam
Abstract
Objective:  Detect  whether  bone  erosion  or  destruction  alters  the ADC value while  discriminating benign from malignant sinonasal masses.
Patients and methods: Twenty five patients were investigated and operated upon  in  this  study.  Preoperative CT  scans  and  diffusion weighted MRI imaging were done within 48 hours prior to surgery. Surgical procedures were done in the form of complete resection or biopsy taking.  The  ADC  values  were  calculated  for  sinonasal lesions associated with bone erosion or destruction detected on CT scanning.  
Results:  Histopathological  diagnosis  revealed  benign  masses  in 44%  and  malignant  tumors  in  56%  of  biopsies.  No significant differences between mean ADC values of the first and second ROI in both benign (P value =0.365) and malignant masses (P value =0.07). Statistical significant difference was found between the ADCL values of benign and malignant sinonasal masses. (P value =0.044).   
Conclusions:  Bone erosion  or  destruction  does  not  alter  the  ADC  value  in differentiating  between  benign  and  malignant  masses. ADC value does not change with bone erosion or destruction.
Keywords
Diffusion-weighted MRI; sinonasal masses; bone erosion; destruction
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