Safety and efficacy of intracameral injection of dexamethasone and moxifloxacin at the end of cataract surgery | ||
| Zagazig University Medical Journal | ||
| Article 12, Volume 28, Issue 6.2, November 2022, Pages 74-80 PDF (299.06 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/zumj.2019.19166.1616 | ||
| Authors | ||
| Hany Abdalhafiz Albialy* 1; Mostafa Mohammed Wagih2; Doaa Mohammed Gouda3; ashraf mahrous Eid4 | ||
| 1Departmemt of ophthalmology,faculity of medicine , Zagazig university0000 | ||
| 2Ophthalmology Department, Zagazig University, Zagazig, Egypt | ||
| 3Zagazig ophthalmic hospital, Zagazig, Egypt | ||
| 4ophthalmology department, faculty of medicine, zagazig university | ||
| Abstract | ||
| Background: To evaluate whether intracameral dexamethasone – moxifloxacin can safely and effectively reduce the postoperative inflammation, guard against endophthalmitis and improve surgical outcomes after cataract surgery. Methods: Prospective randomized comparative study included 200 eyes of 200 Patients underwent uncomplicated phacoemulsification . 100 eyes were injected intracamerally with 0.1 ml moxifloxacin 0.5% and 0.4 mg dexamethasone at the end of surgery while the other 100 eyes as a control group received intracameral placebo injection. Outcomes were measured on first postoperative day and weekly for one month by visual acuity assessment, slit lamp examination, intraocular pressure , endothelial cell density and any postoperative complications. Results: Aqueous cells on the first postoprative day in group I : five eyes had 2+, and 7 eyes had 1+ with no eyes of +3 or more. After 1 week , all eyes had no anterior chamber cells. In group II, the first postoperative day showed 11 eyes with 3+, 15 eyes had 2+, 8 eyes had 1+. One week postoperatively , only 3 eyes had +1 aquous cells. All eyes of both groups had no detected anterior chamber cells at subsequent follow up visits. The mean postoperative endothelial cell density in injectedgroup was 2274.15 cells/mm2 ±330.09. after one month . There was no significant effect on IOP values with no detected long-term complications . Conclusion: Intracameral dexamethasone- moxifloxacin injected at the end of cataract surgery reduces the postoperative AC cells significantly and improves patient's compliance in early postoperative follow period with no risk of IOP elevation. | ||
| Keywords | ||
| Keywords: cataract surgery; intracameral; dexamethasone; moxifoxacin | ||
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