PHYTOCHEMICAL AND BIOLOGICAL STUDY OF VANGUERIA EDULIS CULTIVATED IN EGYPT | ||
Bulletin of Pharmaceutical Sciences Assiut University | ||
Article 6, Volume 35, Issue 1, June 2012, Pages 67-81 PDF (339.96 K) | ||
Document Type: Original Article | ||
DOI: 10.21608/bfsa.2012.64603 | ||
Authors | ||
Daoud W. Bishay; Enaam Y. Backheet; Yaser Gouda* ; Shaymaa M. Mostafa | ||
Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt | ||
Abstract | ||
Fractionation and purification of the alcoholic extract of the leaves and stem -bark of Vangueria edulis cultivated in Egypt afforded thirteen compounds identified as: β-sitosterol acetate (1), stigmasterol (2), palmitic acid (3), scopoletin (4), p-coumaric acid (5), protocatechuic acid (6), esculetin (7), ethyl 1-O-glucosyl-4-O-(E) caffeoyl quinate (8), kaempferol 3-O-rhamnoside, 7-O-rutinoside (9), β-sitosterol (10), ceryl alcohol (11), vanillic acid (12) and β-sitosterol-3-O-β-D-glucopyranoside (13). Identification of these compounds has been established by physical, chemical and spectral data as well as comparison with authentic samples. Compounds 8 and 9 are firstly reported from a natural source while the rest of the compounds have been isolated for the first time from the genus Vangueria. The LD50, antibacterial, antifungal, anti-inflammatory, antipyretic and the effect on CNS were studied. | ||
Statistics Article View: 214 PDF Download: 186 |