Synthesis, Molecular Modeling and Biological Evaluation of Indeno[1,2-b]quinoxaline Derivatives as Antifungal and Antibacterial Agents
Abd El salam, H., El-Bendary, M., Ibrahim, M., El-Samahy, F. (2020). Synthesis, Molecular Modeling and Biological Evaluation of Indeno[1,2-b]quinoxaline Derivatives as Antifungal and Antibacterial Agents. EKB Journal Management System, 63(7), 2577-2590. doi: 10.21608/ejchem.2020.21366.2275
Hayam A. Abd El salam; Magda A. El-Bendary; Medhat Ibrahim; Fatma A. El-Samahy. "Synthesis, Molecular Modeling and Biological Evaluation of Indeno[1,2-b]quinoxaline Derivatives as Antifungal and Antibacterial Agents". EKB Journal Management System, 63, 7, 2020, 2577-2590. doi: 10.21608/ejchem.2020.21366.2275
Abd El salam, H., El-Bendary, M., Ibrahim, M., El-Samahy, F. (2020). 'Synthesis, Molecular Modeling and Biological Evaluation of Indeno[1,2-b]quinoxaline Derivatives as Antifungal and Antibacterial Agents', EKB Journal Management System, 63(7), pp. 2577-2590. doi: 10.21608/ejchem.2020.21366.2275
Abd El salam, H., El-Bendary, M., Ibrahim, M., El-Samahy, F. Synthesis, Molecular Modeling and Biological Evaluation of Indeno[1,2-b]quinoxaline Derivatives as Antifungal and Antibacterial Agents. EKB Journal Management System, 2020; 63(7): 2577-2590. doi: 10.21608/ejchem.2020.21366.2275

Synthesis, Molecular Modeling and Biological Evaluation of Indeno[1,2-b]quinoxaline Derivatives as Antifungal and Antibacterial Agents

Egyptian Journal of Chemistry
Article 14, Volume 63, Issue 7, July 2020, Page 2577-2590  XML PDF (1.7 MB)
Document Type: Original Article
DOI: 10.21608/ejchem.2020.21366.2275
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Authors
Hayam A. Abd El salamorcid 1; Magda A. El-Bendary2; Medhat Ibrahim3; Fatma A. El-Samahy email 1
1Green Chemistry Department, Chemical Industrial Research Division, National Research Centre.
2Microbial Chemistry Department, Genetic Engineering and Biotechnology Division, National Research Centre.
3Spectroscopy Department, National Research Centre, 33 El-Bohouth St, Dokki, Giza, Egypt, P.O.12622.
Abstract
The (11H-indeno[1,2-b]quinoxalin-11-ylidene)thiocarbohydrazonewere synthesized and consequently some new novel structures were obtained in a good yields. Their chemical structures were assigned by means of spectral analysis. Molecular modeling at B3LYP/6-31 g (d, p) is utilized to calculate both the optimized structure and vibrational spectra of some studied structures. A promising antimicrobial result was obtained from the new synthesized compounds.
Keywords
11Н-Indeno [1; 2-b]quinoxalin-2-one; Thiocarbohydrazides; 2- Chloroacetamide derivatives; Molecular modeling; antimicrobial activity
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