SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF NEW N-ETHYL-N-METHYL BENZENE SULFONAMIDE DERIVATIVES | ||||
Al-Azhar Journal of Pharmaceutical Sciences | ||||
Article 1, Volume 49, Issue 1 - Serial Number 49, March 2014, Page 35-43 PDF (437.71 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/ajps.2014.6954 | ||||
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Author | ||||
Ahmed El-Morsy | ||||
Organic Chemistry Department, faculty of Pharmacy (Boy’s) Al-Azhar University, Nasr City, Cairo, Egypt. | ||||
Abstract | ||||
This article describes the synthesis of some novel sulfonamide having the biologically active hydrazones 1,3,4-thiadiazoles and 4-oxothiazolidines moieties 2-4, 7 and 10-13 respectively. Starting with 4-acetyl-N-ethyl-N-methyl benzene sulfonamide (1). The structure of the newly synthesized compounds was confirmed by elemental analysis, IR, 1H-NMR and mass spectral data. | ||||
Keywords | ||||
Sulfonamide; hydrazone; 1; 3; 4-thiazdiazine and oxothiazolidine | ||||
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