SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF SOME NEW COUMARIN, PYRIDINE, 1,2,3-TRIAZOLE, THIAZOLIDINONE, PYRAZOLOTRIAZINE, THIOPHENE AND THIAZOLE DERIVATIVES BEARING CARBONYLHYDRAZONOETHYLPHENYLTOSYLATE MOIETY | ||
Al-Azhar Bulletin of Science | ||
Article 14, Volume 2011, Issue 12, December 2011, Pages 165-180 PDF (256.97 K) | ||
Document Type: Original Article | ||
DOI: 10.21608/absb.2011.7025 | ||
Authors | ||
MAHMOUD M. ABDELALL* 1; SHABAN I. MOHAMED2; AHMED H. HALAWA1; AHMED A. HASSAN1; MOHAMED A. ELNASSAG1 | ||
1Chemistry Department, Faculty of Science, Al-Azhar University, Nasr City, Cairo, Egypt. | ||
2Technology Engineering Institute, Tamoh, Giza, Egypt. | ||
Abstract | ||
A number of novel coumarin (4), pyridinone (5a,b), thiophenopyridinone (6), 1,2,3-triazole (7), pyrazolotriazine (10), thiazole (11,14a,b,15), thiophene (12), thiazolidinone (20,21,23) derivatives were synthesized via interaction of 4-(1-(2-(2-cyanoacetyl)hydrazono)ethyl)phenyltosylate (3) with different nucleophilic reagents. The structures of the newly synthesized compounds were confirmed by elemental analyses IR, 1H-NMR and mass spectral data. All compounds were evaluated for their antimicrobial activities. | ||
Keywords | ||
yanoacetylhydrazonoethylphenyltosylate; Pyridine; thiazole; Coumarin; THIOPHENE; pyrazolotriazine; thiazolidinone | ||
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