serum Interleukin-6 level a risk factor in pathogenesis of otitis media with effusion in children?
Abo Elmagd, E., Elebidi, A., Nour Eldin, E., El Tahan, A. (2020). serum Interleukin-6 level a risk factor in pathogenesis of otitis media with effusion in children?. EKB Journal Management System, 6(1), 37-42. doi: 10.21608/ejnso.2020.70572
Essam A. Abo Elmagd; Abdullah M Elebidi; Esraa Nour Eldin; Abd Elrahman El Tahan. "serum Interleukin-6 level a risk factor in pathogenesis of otitis media with effusion in children?". EKB Journal Management System, 6, 1, 2020, 37-42. doi: 10.21608/ejnso.2020.70572
Abo Elmagd, E., Elebidi, A., Nour Eldin, E., El Tahan, A. (2020). 'serum Interleukin-6 level a risk factor in pathogenesis of otitis media with effusion in children?', EKB Journal Management System, 6(1), pp. 37-42. doi: 10.21608/ejnso.2020.70572
Abo Elmagd, E., Elebidi, A., Nour Eldin, E., El Tahan, A. serum Interleukin-6 level a risk factor in pathogenesis of otitis media with effusion in children?. EKB Journal Management System, 2020; 6(1): 37-42. doi: 10.21608/ejnso.2020.70572

serum Interleukin-6 level a risk factor in pathogenesis of otitis media with effusion in children?

Egyptian Journal of Neck Surgery and Otorhinolaryngology
Article 3, Volume 6, Issue 1, March 2020, Page 37-42  XML PDF (186.57 K)
Document Type: Original Article
DOI: 10.21608/ejnso.2020.70572
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Authors
Essam A. Abo Elmagd; Abdullah M Elebidi1; Esraa Nour Eldin2; Abd Elrahman El Tahan3
1Biochemistry Faculty of Medicine - Aswan University
2M.B.B.CH Faculty of Medicine - Assuit Universit.
3Otolaryngology, faculty of medicine, Aswan University, Egypt
Abstract
Objective: The aim of the study was to detect the serum level of cytokine interleukin-6 (IL-6) in children with persistent Otitis media with effusion (OME).
Patients and methods: 50 children with OME divided into 3 groups, a group I consisted of 30 children who had persistent otitis media with effusion and did not improve by medical and surgical treatment. The age range of 5.8 ± 3. 4 years. Group (II) consisted of 20 children who had two or fewer OME episodes per year and improved by medical treatment and did not have a history of tubes insertion. The age range 6.3± 2.9 years. Group III consisted of 52 normal patients with similar age and sex as a control group.
Results: There was no significant difference between group I and group II. There was a significance difference between each group and normal patients.
Conclusion: The result of the present study suggesting that pro-inflammatory cytokine level Il-6 (IL-6) is significantly increased with persistent OME in children in comparison with normal patients.
Keywords
Interleukin-6; Otitis media – Effusion- Pathogenesis
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