ONE-POT SYNTHESIS AND ANTIMICROBIAL SCREENING OF NEW [1,5] –BENZODIAZEPINE DERIVATIVES CATALYZED BY TBAB | ||||
| Al-Azhar Journal of Pharmaceutical Sciences | ||||
| Article 12, Volume 46, Issue 2 - Serial Number 46, September 2012, Page 161-168 PDF (469.26 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ajps.2012.7143 | ||||
 View on SCiNiTO | ||||
| Author | ||||
| Kamal El-Gaml | ||||
| Organic Chemistry Department, Al-Azher University, Nasr City , Cairo,11884, Egypt | ||||
| Abstract | ||||
| A new [1,5]-benzodiazepines (VI) were synthesized by the reaction of o-phenylenediamine with 2-chloro-3-acetylquinoline in the presence of tetrabutyl ammonium bromide (TBAB) in short reaction time with excellent yield. | ||||
| Keywords | ||||
| tetrabutyl ammonium bromide; [1; 5]- Benzodiazepine; 2-chloro-3-acetylquinoline derivatives; o-phenelendiamine | ||||
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