THE UTILITY OF 1-CYANOACETYL-4-(4-ETHOXYPHENYL) THIO-SEMICARBAZIDE FOR SYNTHESIS OF PYRAZOLE, TRIAZOLE, THIAZOLE, PYRIDINE AND CHROMENE DERIVATIVES | ||
Al-Azhar Bulletin of Science | ||
Article 6, Volume 2011, Issue 6, June 2011, Pages 85-96 PDF (423.47 K) | ||
Document Type: Original Article | ||
DOI: 10.21608/absb.2011.7179 | ||
Authors | ||
H. KH. THABET* 1; M. H. HELAL1; M. A. SALEM1; A. A. FARRAG2 | ||
1Chemistry Department, Faculty of Science, Al-Azhar University, 11284 Nasr City, Cairo, Egypt | ||
2Chemistry Department, Faculty of Science (Girls), Al-Azhar University, Nasr City, Cairo, Egypt | ||
Abstract | ||
The reaction of cyanoacetic acid hydrazide with 4-ethoxyphenylisothiocyanate gave the thiosemicarbazide derivative (3). The latter underwent a series of heterocyclization reactions when it reacts with either α-halo compounds, thioglycolic acid, acetylacetone, cinnamonitrile, or o-hydroxy aldehydes | ||
Keywords | ||
1, 2, 4-triazoles; Thiosemicarbazide derivative; pyrazole; Thiazoles; tri-azolylthiazolone; Chromenes | ||
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