Synthesis, Characterization and Antimicrobial Activity of Novel Pyrrolidine-3-Carbonitrile Derivatives, | ||
| Egyptian Journal of Chemistry | ||
| Article 1, Volume 61, Issue 3, May and June 2018, Pages 391-400 PDF (1.89 M) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejchem.2018.3115.1263 | ||
| Authors | ||
| M. F. El-Mansy1; Leila Boulos* 1; M. E. Mohram2 | ||
| 1Department of Organometallic and Organometalloid Chemistry, National Research Centre, 33 El-Bohouth St.(former EL Tahrir st.), P.O. 12622, Dokki, Giza, Egypt | ||
| 2Microbial Chemistry Department, National Research Centre, 33 El-Bohouth St.(former EL Tahrir st.), P.O. 12622, Dokki, Giza, Egypt | ||
| Abstract | ||
| Newly synthesized pyrrolidine-3-carbonitrile derivatives were evaluated as antimicrobial activity. The structures of these derivatives were derived from reactions of 1-(4-methoxyphenyl)-4-oxopyrrolidine-3-carbonitrile with stabilized phosphorus ylides, Wittig-Horner reagents, trialkylphosphites, as well as tris(dialkylamino)phosphines | ||
| Keywords | ||
| : Pyrrolidine; Wittig; Trialkylphosphite; alkene; antimicrobial activity | ||
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