SYNTHESIS AND BIOLOGICAL ACTIVITIES OF SOME 3-(AMINO OR ARYLIDINE)-2-PYRIDINYL-4(3H)-QUINAZOLINONE AND SOME OF THEIR COPPER COMPLEXES | ||
Al-Azhar Bulletin of Science | ||
Article 1, Volume 2010, Issue 6, June 2010, Pages 1-20 PDF (201.37 K) | ||
Document Type: Original Article | ||
DOI: 10.21608/absb.2010.7333 | ||
Authors | ||
MOHSEN M. ALY* 1; WAHID M. BASYOUNI2; YAHIA A. MOHAMED1; KHAIRY A. EL-BAYOUKI2; SAMIR Y. ABBAS2 | ||
1Department of Chemistry, Faculty of Science, Al-Azhar University, Cairo, Egypt | ||
2National Research Centre, Dokki, Cairo, Egypt | ||
Abstract | ||
Several 4(3H)-quinazolinones containing pyridine moiety were synthesized starting from substituted anthranilic acid derivatives. Copper complexes of 3-amino-2-pyridinyl-4(3H)-quinazolinones and some of their derivatives were synthesized and characterized. The synthesized compounds were screened for their anticonvulsant, analgesic, antitumor, as well as, their antimicrobial activities. | ||
Keywords | ||
4(3H)-Quinazolinones; Copper complexes; Anticonvulsant; analgesic; Antitumor and antimicrobial activities | ||
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