HETEROAROMATIZATION WITH SULFONAMIDO PHENYL ETHANONE: PART (IV). SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF NEW N-ETHYL-N-METHYLBENZENESULFONAMIDE, 1,3,4-THIADIAZOLE, 1,3,4-THIADIAZINE, 4-OXOTHIAZOLIDINE AND PYRAZOLO[5,1-c][1,2,4]TRIAZINE DERIVATIVES | ||||
Al-Azhar Bulletin of Science | ||||
Article 24, Volume 2010, Issue 12, December 2010, Page 325-344 PDF (177.48 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/absb.2010.7385 | ||||
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Authors | ||||
MAHMOUD M. ABDELALL* 1; MAHMOUD S. BASHANDY1; AHMAD M. EL-MORSY2 | ||||
1Chemistry Department, Faculty of Science, Al -Azhar University, Cairo, Egypt. | ||||
2Organic Chemistry Department, Faculty of pharmacy (Boy's), Al-Azhar University, Nasr City, Cairo, Egypt | ||||
Abstract | ||||
This article describes the synthesis of some novel sulfonamide having the biologically active, hydrazones 7-11,1,3,4-thiadiazoles 15-18, 20,1,3,4-thiadiazine 19, 4-oxothiazolidines 21, 26-29 andpyrazolo[5,1-c][1,2,4]triazine 32 moieties starting with 4-acetyl-N-ethyl-N-methylbenzenesulfonamide (1). The structure of the newly synthesized compounds was confirmed by elemental analysis, IR, 1H NMR, and mass spectral data. | ||||
Keywords | ||||
1, 3, 4-thiadiazole,; Sulfonamide; 1, 3, 4-thiadiazine; hydrazone; pyrazolo[5, 1-c][1, 2, 4]triazine; 4-oxothiazolidine | ||||
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