Qualitative GC-MS analysis and antimicrobial activity of volatiles from Carthamus lanatus (L.) growing in Egypt
Abu ElKhair, R., Omran, G., Yasser, M., Seif ElDin, A. (2020). Qualitative GC-MS analysis and antimicrobial activity of volatiles from Carthamus lanatus (L.) growing in Egypt. EKB Journal Management System, 4(1), 6-12. doi: 10.21608/rpbs.2019.15957.1036
Rasha Mohamed Abu ElKhair; Gamal Abd ElHay Omran; Mariam Yasser; Ahmed Adel Seif ElDin. "Qualitative GC-MS analysis and antimicrobial activity of volatiles from Carthamus lanatus (L.) growing in Egypt". EKB Journal Management System, 4, 1, 2020, 6-12. doi: 10.21608/rpbs.2019.15957.1036
Abu ElKhair, R., Omran, G., Yasser, M., Seif ElDin, A. (2020). 'Qualitative GC-MS analysis and antimicrobial activity of volatiles from Carthamus lanatus (L.) growing in Egypt', EKB Journal Management System, 4(1), pp. 6-12. doi: 10.21608/rpbs.2019.15957.1036
Abu ElKhair, R., Omran, G., Yasser, M., Seif ElDin, A. Qualitative GC-MS analysis and antimicrobial activity of volatiles from Carthamus lanatus (L.) growing in Egypt. EKB Journal Management System, 2020; 4(1): 6-12. doi: 10.21608/rpbs.2019.15957.1036

Qualitative GC-MS analysis and antimicrobial activity of volatiles from Carthamus lanatus (L.) growing in Egypt

Records of Pharmaceutical and Biomedical Sciences
Article 2, Volume 4, Issue 1, March 2020, Page 6-12  XML PDF (914.6 K)
Document Type: Original Article
DOI: 10.21608/rpbs.2019.15957.1036
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Authors
Rasha Mohamed Abu ElKhair email orcid 1; Gamal Abd ElHay Omran2; Mariam Yasser3; Ahmed Adel Seif ElDin4
1Pharmacognosy department, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt
2Biochemistry department, Faculty of Pharmacy, Damanhour University, Damanhour, Egypt
3Pharmacognosy Department, Faculty of Pharmacy, Damanhour University, Damanhour, Egypt
4Pharmacognosy Department, Faculty of Pharmacy, Alexandria University
Abstract
The volatiles of both fresh aerial parts and flowers of Carthamus lanatus L. plant growing in Egypt were isolated by hydro-distillation method. The obtained volatiles were subsequently subjected to qualitative analysis by Gas chromatography accompanied by mass specctrometic analysis (GC-MS) , which in turn revealed the presence of forty four compounds. The interpretation of the isolated compounds was carried out depending on comparison of their mass spectra with those saved in instrument library, alongside the data reported in literature. On the other hand, a comparative investigation between the Egyptian and Bulgarian species was carried out, which in turn revealed great differences. Antimicrobial screening (using agar diffusion method) of the screened volatiles of Egyptian plant was also carried out, that labored into promising results of potent activity exhibited against different bacteria and fungi compared with gentamycin and ketoconazole antimicrobial standards. it is worth mentioned that our study is the first study of the Egyptian Carthamus lanatus Plant.
Keywords
Carthamus lanatus; GC-MS; Asteraceae; antimicrobial activity; agar diffusion method
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