SYNTHESIS AND ANTICONVULSANT ACTIVITY OF SOME N-SUBSTITUTED-N'-(2-METHYL-4-OXOQUINAZOLIN-3-YL) OXAMIDES | ||
Bulletin of Pharmaceutical Sciences Assiut University | ||
Article 6, Volume 9, Issue 2, December 1986, Pages 78-91 PDF (420.32 K) | ||
Document Type: Original Article | ||
DOI: 10.21608/bfsa.1986.74578 | ||
Authors | ||
A. M. Abdel-Alim1; S. A. Hussein1; H. I. El-Bitar2; R. A. Abdel-Aal2 | ||
1Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Assiut University, Assiut, Egypt | ||
2Department of Pharmacology, Faculty of Medicine, Assiut University, Assiut, Egypt | ||
Abstract | ||
Fourteen new oxamides were synthesized by amidation of ethyl N-(2-methyl-4-oxoquinazolin-3-yl) oxamate with the appropriate amines. Preliminary anticonvulsant activity of five oxamides was evaluated, Correlation of activity with structure of the test compounds is also discussed. | ||
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