SYNTHESIS AND ANTICONVULSANT ACTIVITY OF SOME N-SUBSTITUTED-N'-(2-METHYL-4-OXOQUINAZOLIN-3-YL) OXAMIDES
Abdel-Alim, A., Hussein, S., El-Bitar, H., Abdel-Aal, R. (1986). SYNTHESIS AND ANTICONVULSANT ACTIVITY OF SOME N-SUBSTITUTED-N'-(2-METHYL-4-OXOQUINAZOLIN-3-YL) OXAMIDES. EKB Journal Management System, 9(2), 78-91. doi: 10.21608/bfsa.1986.74578
A. M. Abdel-Alim; S. A. Hussein; H. I. El-Bitar; R. A. Abdel-Aal. "SYNTHESIS AND ANTICONVULSANT ACTIVITY OF SOME N-SUBSTITUTED-N'-(2-METHYL-4-OXOQUINAZOLIN-3-YL) OXAMIDES". EKB Journal Management System, 9, 2, 1986, 78-91. doi: 10.21608/bfsa.1986.74578
Abdel-Alim, A., Hussein, S., El-Bitar, H., Abdel-Aal, R. (1986). 'SYNTHESIS AND ANTICONVULSANT ACTIVITY OF SOME N-SUBSTITUTED-N'-(2-METHYL-4-OXOQUINAZOLIN-3-YL) OXAMIDES', EKB Journal Management System, 9(2), pp. 78-91. doi: 10.21608/bfsa.1986.74578
Abdel-Alim, A., Hussein, S., El-Bitar, H., Abdel-Aal, R. SYNTHESIS AND ANTICONVULSANT ACTIVITY OF SOME N-SUBSTITUTED-N'-(2-METHYL-4-OXOQUINAZOLIN-3-YL) OXAMIDES. EKB Journal Management System, 1986; 9(2): 78-91. doi: 10.21608/bfsa.1986.74578

SYNTHESIS AND ANTICONVULSANT ACTIVITY OF SOME N-SUBSTITUTED-N'-(2-METHYL-4-OXOQUINAZOLIN-3-YL) OXAMIDES

Bulletin of Pharmaceutical Sciences Assiut University
Article 6, Volume 9, Issue 2, December 1986, Pages 78-91    PDF (420.32 K)
Document Type: Original Article
DOI: 10.21608/bfsa.1986.74578
Authors
A. M. Abdel-Alim1; S. A. Hussein1; H. I. El-Bitar2; R. A. Abdel-Aal2
1Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Assiut University, Assiut, Egypt
2Department of Pharmacology, Faculty of Medicine, Assiut University, Assiut, Egypt
Abstract
Fourteen new oxamides were synthesized by amidation of ethyl N-(2-methyl-4-oxoquinazolin-3-yl) oxamate with the appropriate amines. Preliminary anticonvulsant activity of five oxamides was evaluated, Correlation of activity with structure of the test compounds is also discussed.
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