Histological evaluation of the ANTIOXIDANT effect of Vitamin E on reversing the negative impact of tartrazine on extraction socket healing. (Randomized controlled trial)
Obeid, R., Abdelmoneim, H., Elsharkawy, R. (2020). Histological evaluation of the ANTIOXIDANT effect of Vitamin E on reversing the negative impact of tartrazine on extraction socket healing. (Randomized controlled trial). EKB Journal Management System, 66(Issue 1 - January (Oral Medicine, X-Ray, Oral Biology & Oral Pathology)), 285-292. doi: 10.21608/edj.2020.77544
Raneem F. Obeid; Hesham S. Abdelmoneim; Radwa T. Elsharkawy. "Histological evaluation of the ANTIOXIDANT effect of Vitamin E on reversing the negative impact of tartrazine on extraction socket healing. (Randomized controlled trial)". EKB Journal Management System, 66, Issue 1 - January (Oral Medicine, X-Ray, Oral Biology & Oral Pathology), 2020, 285-292. doi: 10.21608/edj.2020.77544
Obeid, R., Abdelmoneim, H., Elsharkawy, R. (2020). 'Histological evaluation of the ANTIOXIDANT effect of Vitamin E on reversing the negative impact of tartrazine on extraction socket healing. (Randomized controlled trial)', EKB Journal Management System, 66(Issue 1 - January (Oral Medicine, X-Ray, Oral Biology & Oral Pathology)), pp. 285-292. doi: 10.21608/edj.2020.77544
Obeid, R., Abdelmoneim, H., Elsharkawy, R. Histological evaluation of the ANTIOXIDANT effect of Vitamin E on reversing the negative impact of tartrazine on extraction socket healing. (Randomized controlled trial). EKB Journal Management System, 2020; 66(Issue 1 - January (Oral Medicine, X-Ray, Oral Biology & Oral Pathology)): 285-292. doi: 10.21608/edj.2020.77544

Histological evaluation of the ANTIOXIDANT effect of Vitamin E on reversing the negative impact of tartrazine on extraction socket healing. (Randomized controlled trial)

Egyptian Dental Journal
Article 13, Volume 66, Issue 1 - January (Oral Medicine, X-Ray, Oral Biology & Oral Pathology), January 2020, Page 285-292  XML PDF (2.01 MB)
Document Type: Original Article
DOI: 10.21608/edj.2020.77544
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Authors
Raneem F. Obeid1; Hesham S. Abdelmoneim2; Radwa T. Elsharkawy1
1Lecturer of Oral Biology, Faculty of Oral and Dental Medicine, Future University in Egypt
2Lecturer of Oral and Maxillofacial Surgery, Faculty of Dentistry, Cairo University
Abstract
One of a synthetic food dye which used worldwide is Tartrazine, it is an orange-colored, water soluble with a potential toxicological risk. Food or drinks containing tartrazine caused sensitivity symptoms. Vitamin E is an essential lipid-soluble vitamin and has well-established antioxidant properties which improve the proliferation, differentiation, and mineralization, and reduced apoptosis of osteoblastic cells.
Aim of this study: to evaluate the effect of tartrazine and co-administration of vitamin E on post extraction socket using histological examination by light microscope.
Materials and methods: Surgical extraction of mandibular first molars were done in a twenty one albino rats, the animals were randomly divided into 3 groups; group I (control), group II given tartrazine and group III given tartrazine and Vitamin E (treated group). The duration of the experiments was 14 days. Histological evaluation was done by H & E and Masson trichrome.
Results: the bone healing of the extraction socket in the Vitamin E treated group was nearly the same as the control group.
Conclusion: Vitamin E has a protective effect as an effective antioxidant on bone healing in post extraction socket and may be useful as a supportive agent in an endless array of dental surgeries.
Keywords
Extraction; Socket; Vitamin E; Tartrazine; antioxidant; food color; bone healing
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