PYRIMIDINETHIONES AS BUILDING BLOCKS IN HETEROCYCLIC SYNTHESIS: SYNTHESIS OF PYRANO[2,3-D]PYRIMIDINE, CHROMENO[2,3-D]PYRIMIDINE, PYRIDO[3',2':5,6]PYRANO[2,3-B]PYRIDINE AND PYRIMIDO[5',4':5,6]PYRANO[2,3-D]PYRIMIDINE
Elian, M., AbdelHafiz, I., AbdElReheim, M. (2014). PYRIMIDINETHIONES AS BUILDING BLOCKS IN HETEROCYCLIC SYNTHESIS: SYNTHESIS OF PYRANO[2,3-D]PYRIMIDINE, CHROMENO[2,3-D]PYRIMIDINE, PYRIDO[3',2':5,6]PYRANO[2,3-B]PYRIDINE AND PYRIMIDO[5',4':5,6]PYRANO[2,3-D]PYRIMIDINE. EKB Journal Management System, 3(2), 51-62. doi: 10.21608/sinjas.2014.78457
Mohamed A. Elian; Ibrahim S. AbdelHafiz; Mohamed A.M. AbdElReheim. "PYRIMIDINETHIONES AS BUILDING BLOCKS IN HETEROCYCLIC SYNTHESIS: SYNTHESIS OF PYRANO[2,3-D]PYRIMIDINE, CHROMENO[2,3-D]PYRIMIDINE, PYRIDO[3',2':5,6]PYRANO[2,3-B]PYRIDINE AND PYRIMIDO[5',4':5,6]PYRANO[2,3-D]PYRIMIDINE". EKB Journal Management System, 3, 2, 2014, 51-62. doi: 10.21608/sinjas.2014.78457
Elian, M., AbdelHafiz, I., AbdElReheim, M. (2014). 'PYRIMIDINETHIONES AS BUILDING BLOCKS IN HETEROCYCLIC SYNTHESIS: SYNTHESIS OF PYRANO[2,3-D]PYRIMIDINE, CHROMENO[2,3-D]PYRIMIDINE, PYRIDO[3',2':5,6]PYRANO[2,3-B]PYRIDINE AND PYRIMIDO[5',4':5,6]PYRANO[2,3-D]PYRIMIDINE', EKB Journal Management System, 3(2), pp. 51-62. doi: 10.21608/sinjas.2014.78457
Elian, M., AbdelHafiz, I., AbdElReheim, M. PYRIMIDINETHIONES AS BUILDING BLOCKS IN HETEROCYCLIC SYNTHESIS: SYNTHESIS OF PYRANO[2,3-D]PYRIMIDINE, CHROMENO[2,3-D]PYRIMIDINE, PYRIDO[3',2':5,6]PYRANO[2,3-B]PYRIDINE AND PYRIMIDO[5',4':5,6]PYRANO[2,3-D]PYRIMIDINE. EKB Journal Management System, 2014; 3(2): 51-62. doi: 10.21608/sinjas.2014.78457

PYRIMIDINETHIONES AS BUILDING BLOCKS IN HETEROCYCLIC SYNTHESIS: SYNTHESIS OF PYRANO[2,3-D]PYRIMIDINE, CHROMENO[2,3-D]PYRIMIDINE, PYRIDO[3',2':5,6]PYRANO[2,3-B]PYRIDINE AND PYRIMIDO[5',4':5,6]PYRANO[2,3-D]PYRIMIDINE

Sinai Journal of Applied Sciences
Article 2, Volume 3, Issue 2, August 2014, Pages 51-62    PDF (226.21 K)
DOI: 10.21608/sinjas.2014.78457
Authors
Mohamed A. Elian* ; Ibrahim S. AbdelHafiz; Mohamed A.M. AbdElReheim
Dept. Chem., Fac. Educ., Suez Canal Univ., Arish, Egypt.
Abstract
A series of new thioxopyrimidine, 4H-pyrans, pyranopyridine and pyranopyrimidine derivatives with expected biological activity have been prepared through the reaction of 6-phenyl-2-thioxo-2,3-dihydropyrimidin-4(5H)-one 4 and 7-Amino-5-(4-chlorophenyl)-4-phenyl-2-thioxo-2,5-dihydro-1H-pyrano[2,3-d]pyrimidine-6-carbonitrile 11b with some electrophilic reagents and nucleophilic reagents. The newly synthesized compounds were characterized by IR, 1H-NMR and mass spectral studies.
Keywords
Thioxopyrimidine; 4H-pyrans; pyranopyridine and pyranopyrimidine
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