The Effect of Metformin upon Spermatogenesis in Mice | ||
| Alexandria Science Exchange Journal | ||
| Article 8, Volume 39, April-June - Serial Number 2, April 2018, Pages 256-259 PDF (288.65 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/asejaiqjsae.2018.8020 | ||
| Authors | ||
| Aalaa M. Ayyad* ; Mohamed A. El-Seehy* | ||
| Department of genetics, faculty of agriculture,Alexandria unniveristy. | ||
| Abstract | ||
| The effect of the drug Metformin has been studied, employing Mice genome ( mus musculus 2n=40) . Three doses 250, 500 and 1000 mg/ml in addition to the negative control were tested. The results obtained has now been reported for the first time; since a significant increases in sperms 10 fold-increases were obtained. It seems probable that such effect might be caused by enhancement of cell division. | ||
| Keywords | ||
| Metformin; sperm; mice genome | ||
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