ALLEVIATING THE HISTOLOGICAL ALTERATIONS OF SOME INTERNAL ORGANS OF RABBITS FED AFLATOXIN-B1 CONTAMINATED DIET VIA Nigella sativa AND VITAMIN C | ||
Journal of Animal and Poultry Production | ||
Article 1, Volume 1, Issue 2, February 2010, Pages 23-33 PDF (370.34 K) | ||
Document Type: Original Article | ||
DOI: 10.21608/jappmu.2010.86090 | ||
Authors | ||
Amal M. Ahmed; Kh. M. El-Meleigy; Manal A. Atwa | ||
Regional Center for Foods and Feeds, Agric. Res. Center, Ministry of Agric., Giza, Egypt. | ||
Abstract | ||
This work was carried out to evaluate the alleviation ability of Nigella sativa (Ns) and or vitamin C for the toxic effect of aflatoxin B1 in rabbits diet. Forty New-Zealand White male rabbits (average body weight 1000 ± 10 g) were used in five experimental groups (8 / group) for 6 weeks. The control group (T1) fed control diet, 2nd group (T2) fed the diet with 200 ppb aflatoxin B1. The 3rd, 4th and 5th group (T3, T4 & T5) fed diets with 200 ppb aflatoxin B1 plus 1% Ns, 500 mg vitamin C/ kg diet and 1% Ns plus 500 mg vitamin C/kg diet, respectively. Results showed that Ns or vitamin C addition can alleviate the negative effect of aflatoxin B1 on internal organs weight and histopathological lesions of liver and kidneys. | ||
Keywords | ||
Rabbits; Aflatoxin B1; Nigella sativa; vitamin C; Histology | ||
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