THE UTILITY OF MICHAEL CONDENSATION FOR THE SYNTHESIS OF MACROMOLECULE SURFACTANTS FROM AZO-NAPHTHOLS AS POSSIBLE ANTIMICROBIALS | ||||
Al-Azhar Bulletin of Science | ||||
Article 3, Volume 2019, Issue 12, December 2019, Page 17-26 PDF (831.5 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/absb.2019.86751 | ||||
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Authors | ||||
Ahmed Hammam ![]() | ||||
1chemistry department, faculty of science, azhar university (boys), cairo | ||||
2Egyptian Petroleum Research Institute (EPRI), Nasr City, Cairo, Egypt | ||||
3Faculty of Science, Al-zhar University, Chemistry Dept., Nasr City, Cairo, Egypt | ||||
Abstract | ||||
((E)-4-(pyridin-3-yldiazenyl)naphthalen-1-ol) and (4-((E)–pyridin-3-yldiazenyl)– 8-((Z)-pyridin-3yldiazenyl)naphthalene-1,5-diol) (IIIa, b) were prepared. Condensation of (IIIa, b) with 2-(pyridin-4ylmethylene) malononitrile (V) under Michael reaction conditions gave the corresponding bezo[h]chromene and dihydrochromene[8,7-h] chromene derivatives (VIa, b). The cationic derivatives for (IIIa, b) and (VIa, b) were obtained by quaternization as (IVa,b) and (VIIa,b). The structures obtained were confirmed form IR, 1HNMR and mass spectra studies. The antimicrobial activities were also studied and have been found that; the cationic dyes (IVa,b) and (VIIa) exhibit promising results against Candida albicans. | ||||
Keywords | ||||
Pyridinyldiazenylnaphthols; cationic azo dyes; antimicrobial activity | ||||
Supplementary Files
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