THE UTILITY OF MICHAEL CONDENSATION FOR THE SYNTHESIS OF MACROMOLECULE SURFACTANTS FROM AZO-NAPHTHOLS AS POSSIBLE ANTIMICROBIALS
Hammam, A., El-Tabei, A., Hegazy, M., Mohamed, M., Sadeq, M. (2019). THE UTILITY OF MICHAEL CONDENSATION FOR THE SYNTHESIS OF MACROMOLECULE SURFACTANTS FROM AZO-NAPHTHOLS AS POSSIBLE ANTIMICROBIALS. EKB Journal Management System, 2019(12), 17-26. doi: 10.21608/absb.2019.86751
Ahmed Hammam; A. S. El-Tabei; M. A. Hegazy; Mahmoud B. Mohamed; M. A. Sadeq. "THE UTILITY OF MICHAEL CONDENSATION FOR THE SYNTHESIS OF MACROMOLECULE SURFACTANTS FROM AZO-NAPHTHOLS AS POSSIBLE ANTIMICROBIALS". EKB Journal Management System, 2019, 12, 2019, 17-26. doi: 10.21608/absb.2019.86751
Hammam, A., El-Tabei, A., Hegazy, M., Mohamed, M., Sadeq, M. (2019). 'THE UTILITY OF MICHAEL CONDENSATION FOR THE SYNTHESIS OF MACROMOLECULE SURFACTANTS FROM AZO-NAPHTHOLS AS POSSIBLE ANTIMICROBIALS', EKB Journal Management System, 2019(12), pp. 17-26. doi: 10.21608/absb.2019.86751
Hammam, A., El-Tabei, A., Hegazy, M., Mohamed, M., Sadeq, M. THE UTILITY OF MICHAEL CONDENSATION FOR THE SYNTHESIS OF MACROMOLECULE SURFACTANTS FROM AZO-NAPHTHOLS AS POSSIBLE ANTIMICROBIALS. EKB Journal Management System, 2019; 2019(12): 17-26. doi: 10.21608/absb.2019.86751

THE UTILITY OF MICHAEL CONDENSATION FOR THE SYNTHESIS OF MACROMOLECULE SURFACTANTS FROM AZO-NAPHTHOLS AS POSSIBLE ANTIMICROBIALS

Al-Azhar Bulletin of Science
Article 3, Volume 2019, Issue 12, December 2019, Pages 17-26    PDF (831.5 K)
Document Type: Original Article
DOI: 10.21608/absb.2019.86751
Authors
Ahmed Hammam* 1; A. S. El-Tabei2; M. A. Hegazy2; Mahmoud B. Mohamed3; M. A. Sadeq3
1chemistry department, faculty of science, azhar university (boys), cairo
2Egyptian Petroleum Research Institute (EPRI), Nasr City, Cairo, Egypt
3Faculty of Science, Al-zhar University, Chemistry Dept., Nasr City, Cairo, Egypt
Abstract
 ((E)-4-(pyridin-3-yldiazenyl)naphthalen-1-ol) and (4-((E)–pyridin-3-yldiazenyl)– 8-((Z)-pyridin-3yldiazenyl)naphthalene-1,5-diol) (IIIa, b) were prepared. Condensation of (IIIa, b) with 2-(pyridin-4ylmethylene) malononitrile (V) under Michael reaction conditions gave the corresponding bezo[h]chromene and dihydrochromene[8,7-h] chromene derivatives (VIa, b). The cationic derivatives for (IIIa, b) and (VIa, b) were obtained by quaternization as (IVa,b) and (VIIa,b). The structures obtained were confirmed form IR, 1HNMR and mass spectra studies. The antimicrobial activities were also studied and have been found that; the cationic dyes (IVa,b) and (VIIa) exhibit promising results against Candida albicans. 
Keywords
Pyridinyldiazenylnaphthols; cationic azo dyes; antimicrobial activity
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