FORMULATION AND STABILITY OF HEPTAMINOL SUPPOSITORIES PART II: Formulation and Characterization of Heptaminol Suppositories | ||
| Bulletin of Pharmaceutical Sciences Assiut University | ||
| Article 4, Volume 7, Issue 2, December 1984, Pages 276-287 PDF (378.95 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/bfsa.1984.89698 | ||
| Authors | ||
| Ali A. Kassem; Mohamed F. El-Miligi; Siham A. Ali | ||
| Department of Pharmaceutics, Faculty of Pharmacy, Cairo University, Cairo, Egypt | ||
| Abstract | ||
| Heptaminol base was formulated in four different suppository bases. The prepared suppositories were subjected to the usual quality-control tests, both when fresh and after shelf-storage for one year. The results of physical examination were so variable that a sharp conclusion to a preferred formula was not possible. However, studies of medicament dissolution revealed that quick and full-dose release of heptaminol was achieved from glycerogelatin-based suppositories. On the other hand, suppositories based with polyethylene glycols have shown a prolonged heptaminol dissolution rates. | ||
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