Gut Microbiota and Type 2 Diabetes Mellitus : What is The Link ? | ||
| Afro-Egyptian Journal of Infectious and Endemic Diseases | ||
| Article 2, Volume 6, Issue 2, June 2016, Pages 112-119 PDF (255.99 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/aeji.2018.9950 | ||
| Author | ||
| Nesma A Ibrahim* | ||
| Internal Medicine Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt | ||
| Abstract | ||
| The rapid increase of cases of type 2 diabetes mellitus (T2DM) in the past decades has made it a widespread metabolic disorder. In addition to well-established risk factors for T2DM, including genetic predisposition, poor physical activity, fetal programming and obesity, an altered configuration of the microbial community in our gut – the microbiota – has emerged as a new candidate that may be linked to T2DM. The aim of this review is to focus the light on the role of gut microbiota as a novel key organ involved in metabolism, and discussing the putative mechanisms linking gut microbiota and T2DM, as well as the therapeutic perspective of intestinal microbiota modulation for T2DM. | ||
| Keywords | ||
| Type 2 diabetes mellitus; gut microbiota | ||
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