EFFECT OF CERTAIN ORGANIC AND INORGANIC ADDITIVES ON THE FLOCCULATION SUSPENSION CONTAINING DIFFERENT SULPHONAMIDES | ||||
Bulletin of Pharmaceutical Sciences Assiut University | ||||
Article 2, Volume 6, Issue 1, June 1983, Page 19-28 PDF (270.5 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/bfsa.1983.100711 | ||||
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Authors | ||||
F. S. Habib; A. E. Aboutaleb; M. A. Attia | ||||
Department of Pharmaceutics, Faculty of Pharmacy, Assiut University, Assiut, Egypt | ||||
Abstract | ||||
The effect of various concentrations of certain organic and inorganic additives on the flocculation of suspensions containing three sulphonamides were investigated. It was found that the sedimentation volume increased relatively in the case of suspensions containing sulphadimidine, then sulphaguanidine which in turn was more than sulphanilamide. It was concluded that the nature of the additives and their concentrations as well as their effects in the cloud point of the surfactant used greatly affected the sedimentation volume. Other factors such as the difference in particle size and density among the three drugs used may also play a part. | ||||
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