Possible role of Non-invasive Continuous Positive Pressure Ventilation In Patients With Overlap Syndrome: Obstructive Sleep Apnea And Chronic Obstructive Pulmonary Disease | ||
| Zagazig University Medical Journal | ||
| Article 24, Volume 28, Issue 5, September 2022, Pages 1087-1093 PDF (476.25 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/zumj.2020.29445.1842 | ||
| Authors | ||
| Rabieh Mohammad Hussein1; Adel Atia A. Moussa2; Reda Mohamed A. Elghamry3; Mohamed Taher Anwar* 4 | ||
| 1Chest Diseases Dept,Faculty of Medicine,Zagazig university, Egypt | ||
| 2Chest Diseases Dept,Faculty of Medicine,Zagazig university,Egypt | ||
| 3Chest Diseases Dept,Faculty of Medicine, Zagazig university, Egypt | ||
| 4Chest diseases dept,faculty of medicine , Zagazig university | ||
| Abstract | ||
| Background: Overlap syndrome (OS), describes the association and simultaneous presence of OSA and COPD, Overlap syndrome has poor clinical prognosis , including increased risk for cardiovascular morbidity, hospitalization due to COPD acute exacerbation, and all-cause mortality. Efficient CPAP treatment has been related to improved survival and decreased hospitalizations. Patients and methods: This study was carried out at sleep lab of Chest Department on 24 patients splitted into two groups Group 1: patients with overlap syndrome (OS) under medical treatment plus CPAP. Group 2: patients with (OS) under medical treatment only. All patients in the study were subjected to full medical history taking, Quality of sleep by Epworth sleepiness scale (ESS). Clinical examination; (general and local), Spirometry, complete lab investigation, polysomnography and Echocardiography. Results: Statistically significant difference was observed between the two groups as regard AHI, nocturnal desaturation, mean pulmonary artery pressure, number of exacerbations per year and frequency of hospital admissions. Conclusion: Patients with CPAP-treated overlap syndrome for a period of one year experienced improving in nocturnal desaturation, mean pulmonary artery pressure and number of exacerbations. | ||
| Keywords | ||
| Apnea/hypopnea index; Overlap Syndrome; Mean pulmonary artery pressure; Nocturnal desaturations; Exacerbations | ||
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