Possible role of Non-invasive Continuous Positive Pressure Ventilation In Patients With Overlap Syndrome: Obstructive Sleep Apnea And Chronic Obstructive Pulmonary Disease
Hussein, R., Moussa, A., Elghamry, R., Anwar, M. (2022). Possible role of Non-invasive Continuous Positive Pressure Ventilation In Patients With Overlap Syndrome: Obstructive Sleep Apnea And Chronic Obstructive Pulmonary Disease. EKB Journal Management System, 28(5), 1087-1093. doi: 10.21608/zumj.2020.29445.1842
Rabieh Mohammad Hussein; Adel Atia A. Moussa; Reda Mohamed A. Elghamry; Mohamed Taher Anwar. "Possible role of Non-invasive Continuous Positive Pressure Ventilation In Patients With Overlap Syndrome: Obstructive Sleep Apnea And Chronic Obstructive Pulmonary Disease". EKB Journal Management System, 28, 5, 2022, 1087-1093. doi: 10.21608/zumj.2020.29445.1842
Hussein, R., Moussa, A., Elghamry, R., Anwar, M. (2022). 'Possible role of Non-invasive Continuous Positive Pressure Ventilation In Patients With Overlap Syndrome: Obstructive Sleep Apnea And Chronic Obstructive Pulmonary Disease', EKB Journal Management System, 28(5), pp. 1087-1093. doi: 10.21608/zumj.2020.29445.1842
Hussein, R., Moussa, A., Elghamry, R., Anwar, M. Possible role of Non-invasive Continuous Positive Pressure Ventilation In Patients With Overlap Syndrome: Obstructive Sleep Apnea And Chronic Obstructive Pulmonary Disease. EKB Journal Management System, 2022; 28(5): 1087-1093. doi: 10.21608/zumj.2020.29445.1842

Possible role of Non-invasive Continuous Positive Pressure Ventilation In Patients With Overlap Syndrome: Obstructive Sleep Apnea And Chronic Obstructive Pulmonary Disease

Zagazig University Medical Journal
Article 24, Volume 28, Issue 5, September 2022, Page 1087-1093  XML PDF (476.25 K)
Document Type: Original Article
DOI: 10.21608/zumj.2020.29445.1842
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Authors
Rabieh Mohammad Hussein1; Adel Atia A. Moussa2; Reda Mohamed A. Elghamry3; Mohamed Taher Anwar email 4
1Chest Diseases Dept,Faculty of Medicine,Zagazig university, Egypt
2Chest Diseases Dept,Faculty of Medicine,Zagazig university,Egypt
3Chest Diseases Dept,Faculty of Medicine, Zagazig university, Egypt
4Chest diseases dept,faculty of medicine , Zagazig university
Abstract
Background: Overlap syndrome (OS), describes the association and simultaneous presence of OSA and COPD, Overlap syndrome has poor clinical prognosis , including increased risk for cardiovascular morbidity, hospitalization due to COPD acute exacerbation, and all-cause mortality. Efficient CPAP treatment has been related to improved survival and decreased hospitalizations.
Patients and methods: This study was carried out at sleep lab of Chest Department on 24 patients splitted into two groups Group 1: patients with overlap syndrome (OS) under medical treatment plus CPAP. Group 2: patients with (OS) under medical treatment only. All patients in the study were subjected to full medical history taking, Quality of sleep by Epworth sleepiness scale (ESS). Clinical examination; (general and local), Spirometry, complete lab investigation, polysomnography and Echocardiography.
Results: Statistically significant difference was observed between the two groups as regard AHI, nocturnal desaturation, mean pulmonary artery pressure, number of exacerbations per year and frequency of hospital admissions.
Conclusion: Patients with CPAP-treated overlap syndrome for a period of one year experienced improving in nocturnal desaturation, mean pulmonary artery pressure and number of exacerbations.
Keywords
Apnea/hypopnea index; Overlap Syndrome; Mean pulmonary artery pressure; Nocturnal desaturations; Exacerbations
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