SOLUBILIZATION OF CARBAMAZEPINE USING HYDROTROPIC AGENTS | ||||
| Bulletin of Pharmaceutical Sciences Assiut University | ||||
| Article 10, Volume 6, Issue 2, December 1983, Page 373-386 PDF (350.58 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/bfsa.1983.102096 | ||||
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| Authors | ||||
| A. E. Aboutaleb; S. M. Ahmed | ||||
| Department of Industrial Pharmacy, Faculty of Pharmacy, Assiut University, Assiut, Egypt | ||||
| Abstract | ||||
| The effect of number of hydrotropic agents be longing to diverse chemical groups, e.g. sugars, sugar alcohols, amides, imides, acids and salts, on the water-solubility of the practically insoluble antiepileptic drug Carbamazepine at 25° was studied. Also, comparison of the solubilizing efficiency of the different hydrotropic agents was performed. It is clearly evident that the solubilizing efficiency of these hydrotropic agents depends upon both type and concentration of the tested additives used in this study. | ||||
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