Prevalence and antimicrobial susceptibility patterns of Staphylococcus aureus isolated from different clinical sources
Abdelghafar, A., Yousef, N., Askora, M. (2020). Prevalence and antimicrobial susceptibility patterns of Staphylococcus aureus isolated from different clinical sources. EKB Journal Management System, 29(1), 1-8. doi: 10.21608/zjps.2020.21790.1006
Aliaa Atef Abdelghafar; Nehal Yousef; Momen Askora. "Prevalence and antimicrobial susceptibility patterns of Staphylococcus aureus isolated from different clinical sources". EKB Journal Management System, 29, 1, 2020, 1-8. doi: 10.21608/zjps.2020.21790.1006
Abdelghafar, A., Yousef, N., Askora, M. (2020). 'Prevalence and antimicrobial susceptibility patterns of Staphylococcus aureus isolated from different clinical sources', EKB Journal Management System, 29(1), pp. 1-8. doi: 10.21608/zjps.2020.21790.1006
Abdelghafar, A., Yousef, N., Askora, M. Prevalence and antimicrobial susceptibility patterns of Staphylococcus aureus isolated from different clinical sources. EKB Journal Management System, 2020; 29(1): 1-8. doi: 10.21608/zjps.2020.21790.1006

Prevalence and antimicrobial susceptibility patterns of Staphylococcus aureus isolated from different clinical sources

Zagazig Journal of Pharmaceutical Sciences
Article 1, Volume 29, Issue 1, June 2020, Page 1-8  XML PDF (758.54 K)
Document Type: Original Article
DOI: 10.21608/zjps.2020.21790.1006
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Authors
Aliaa Atef Abdelghafar email 1; Nehal Yousef2; Momen Askora1
1Microbiology and immunology, faculty of pharmacy, zagazig university, egypt
2Microbviology and Immunology department, faculty of pharmacy, Zagazig University, Zagazig, Egypt
Abstract
Staphylococcus aureus is a Gram positive bacterium living as a commensal on skin, mouth and upper respiratory system, making it a risk factor for opportunistic and nosocomial infections. It is the major cause of skin, bone, pneumonia, soft tissue, and urinary tract infections and other invasive infections in both the community and hospital settings. High prevalence of Methicillin-Resistant Staphylococcus aureus (MRSA) strains between staphylococcal isolates is very problematic. MRSA strains are common causes of nosocomial infections and are associated with increased morbidity and mortality. The aim of this study is to characterize prevalence of MRSA isolates and determine antibiotic susceptibility patterns of S. aureus clinical isolates toward various antibiotics by disc diffusion method. S. aureus isolates showed high resistance to both β-lactams and tetracycline and intermediate resistance to gentamycin, azithromycin and erythromycin. However, low bacterial resistance was noted against chloramphenicol, ciprofloxacin, clindamycin and sulphamethoxazole-trimethoprim. S. aureus isolates exhibited a higher sensitivity toward linezolid and vancomycin. The current study indicates that linezolid and vancomycin are the most effective antistaphylococcal drugs.
Keywords
Staphylococcus aureus; Multidrug Resistance; MRSA; Antibiotic Susceptibility
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