QUINAZOLINONE DERIVATIVES OF BIOLOGICAL INTEREST. II. SYNTHESIS AND ANTIBACTERIAL ACTIVITY OF CERTAIN 3-ARYL-2-(-ARYLSULPHONYLHYDRAZINOMETHY-4(3H)-QUINAZOLINONES | ||||
| Bulletin of Pharmaceutical Sciences Assiut University | ||||
| Article 10, Volume 3, Issue 1, 1980, Page 116-124 PDF (287.59 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/bfsa.1980.104722 | ||||
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| Authors | ||||
| A. M. Abdel-Aleem1; A. F. Abdel-Ghaffer2 | ||||
| 1Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Assiut University, Assiut, Egypt | ||||
| 2Department of Microbiology, Faculty of Medicine, Assiut University, Assiut, Egypt | ||||
| Abstract | ||||
| Twenty five new quinazolinone derivatives were synthesized. Structure of these compounds was established by microanalysis, UV and IR spectrometry, Antibacterial activity of the prepared compounds was determined in comparison to sulphanilamide against four microorganisms. Fifteen compounds exhibited measurable antibacterial activity especially towards Staph. aureus. | ||||
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