COLORIMETRIC DETERMINATION OF CERTAIN SYMPATHOMIMETIC DRUGS
El-Shabouri, S. (1979). COLORIMETRIC DETERMINATION OF CERTAIN SYMPATHOMIMETIC DRUGS. EKB Journal Management System, 2(1), 77-89. doi: 10.21608/bfsa.1979.104853
Salwa R. El-Shabouri. "COLORIMETRIC DETERMINATION OF CERTAIN SYMPATHOMIMETIC DRUGS". EKB Journal Management System, 2, 1, 1979, 77-89. doi: 10.21608/bfsa.1979.104853
El-Shabouri, S. (1979). 'COLORIMETRIC DETERMINATION OF CERTAIN SYMPATHOMIMETIC DRUGS', EKB Journal Management System, 2(1), pp. 77-89. doi: 10.21608/bfsa.1979.104853
El-Shabouri, S. COLORIMETRIC DETERMINATION OF CERTAIN SYMPATHOMIMETIC DRUGS. EKB Journal Management System, 1979; 2(1): 77-89. doi: 10.21608/bfsa.1979.104853

COLORIMETRIC DETERMINATION OF CERTAIN SYMPATHOMIMETIC DRUGS

Bulletin of Pharmaceutical Sciences Assiut University
Article 7, Volume 2, Issue 1, 1979, Page 77-89  XML PDF (448.18 K)
Document Type: Original Article
DOI: 10.21608/bfsa.1979.104853
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Author
Salwa R. El-Shabouri
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Assiut University, Assiut, Egypt
Abstract
A rapid, simple and highly sensitive spectrophotometric method for the determination of oxiderine tartrate, etilefrine hydrochloride, metaraminol bitartrate, orciprenaline sulphate and isoprenaline sulphate is described. The method depends on the reaction of aqueous solution of these drugs with the diazotized 5-chloro-2,4-dinitroaniline in alkaline medium to give a highly coloured product with characteristic lmax for each drug in the range of 420-550 nm. The colour produced in all cases obeys Beer's law. This method is suitable for the analysis of these drugs in pure forms and in pharmaceutical preparations without prior separation.
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