Serum 25-hydroxyvitamin D concentration in Children with Lower Respiratory Tract Infection | ||||
| International Journal of Medical Arts | ||||
| Article 12, Volume 2, Issue 4, October 2020, Page 757-762 PDF (2.08 MB) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ijma.2020.21996.1074 | ||||
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| Authors | ||||
Asmaa Salah Barania  1; Elbakry Mohammed Tharwat Elbakry2; Hany Abdel-Hady El-khaleegy2; Sabah Ibrahim Abdel-Raheem3
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| 1Department of Pediatrics, Damanhour Teaching Hospital, Ministry of Health, Egypt | ||||
| 2Department of Pediatrics, Damietta Faculty of Medicine Al-Azhar University, Egypt | ||||
| 3Department of Clinical Pathology, Damietta Faculty of Medicine Al-Azhar University, Egypt | ||||
| Abstract | ||||
| Background: Vitamin D plays a critical role in the human body. Its deficiency had been proposed to play a role in lower respiratory tract infections [LRTIs], which responsible for 18% of deaths in young children. Aim of the work: The purpose of this study was to assess vitamin D concentrations in children with lower respiratory tract infections. Patients and Methods:After obtaining approval of the ethics committee, a prospective case control study was conducted in pediatric department, Damietta Faculty of Medicine, Al-Azhar University Hospital on children with lower respiratory tract infections and comparing 25-hydroxyvitamin D level between them and normal matched control from December 2018 to September 2019 include 140 children, Group A: 70 cases children had lower respiratory tract infections [LRTIs] either isolated pneumonia or associated with sepsis. Group B: matched with 70 healthy subjects. Results: There was significant reduction of vitamin D among study group children when compared to control group [13.68±5.50 s 40.64±4.76 ng/dl respectively]. There was no significant association between type of infection and vitamin D levels. However, all children with bronchitis had sufficient vitamin D levels. There were vitamin D-deficiency in 64.3% while No one was deficient vitamin D among control group. Conclusion: Children with acute lower respiratory tract infection had significant reduction in vitamin D levels. The reduction had no significant association with the type of infection. | ||||
| Keywords | ||||
| 25-hydroxyvitamin D; Lower respiratory tract infection; Pneumonia; Bronchiolitis; Bronchitis | ||||
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