Assessment of 3-Monochloro 1, 2-Propanediol in some Egyptian Foods and Its Impact on Liver and Renal Toxicity in Rats تقدير 3- أحادى کلور بروبان 2،1 داى ول فى بعض الاغذية المصرية وتأثيرة على سمية الکبد والکلى فى الجرذان
Kandeel, A., Abd El-Rahman, A., Elsanhoty, R., Al-Saman, M., El-Hadary, A. (2020). Assessment of 3-Monochloro 1, 2-Propanediol in some Egyptian Foods and Its Impact on Liver and Renal Toxicity in Rats تقدير 3- أحادى کلور بروبان 2،1 داى ول فى بعض الاغذية المصرية وتأثيرة على سمية الکبد والکلى فى الجرذان. EKB Journal Management System, 11(6), 181-187. doi: 10.21608/jacb.2020.106197
Asmaa Kandeel; A. A. Abd El-Rahman; R. M. Elsanhoty; M. A. Al-Saman; Abdalla El-Hadary. "Assessment of 3-Monochloro 1, 2-Propanediol in some Egyptian Foods and Its Impact on Liver and Renal Toxicity in Rats تقدير 3- أحادى کلور بروبان 2،1 داى ول فى بعض الاغذية المصرية وتأثيرة على سمية الکبد والکلى فى الجرذان". EKB Journal Management System, 11, 6, 2020, 181-187. doi: 10.21608/jacb.2020.106197
Kandeel, A., Abd El-Rahman, A., Elsanhoty, R., Al-Saman, M., El-Hadary, A. (2020). 'Assessment of 3-Monochloro 1, 2-Propanediol in some Egyptian Foods and Its Impact on Liver and Renal Toxicity in Rats تقدير 3- أحادى کلور بروبان 2،1 داى ول فى بعض الاغذية المصرية وتأثيرة على سمية الکبد والکلى فى الجرذان', EKB Journal Management System, 11(6), pp. 181-187. doi: 10.21608/jacb.2020.106197
Kandeel, A., Abd El-Rahman, A., Elsanhoty, R., Al-Saman, M., El-Hadary, A. Assessment of 3-Monochloro 1, 2-Propanediol in some Egyptian Foods and Its Impact on Liver and Renal Toxicity in Rats تقدير 3- أحادى کلور بروبان 2،1 داى ول فى بعض الاغذية المصرية وتأثيرة على سمية الکبد والکلى فى الجرذان. EKB Journal Management System, 2020; 11(6): 181-187. doi: 10.21608/jacb.2020.106197

Assessment of 3-Monochloro 1, 2-Propanediol in some Egyptian Foods and Its Impact on Liver and Renal Toxicity in Rats تقدير 3- أحادى کلور بروبان 2،1 داى ول فى بعض الاغذية المصرية وتأثيرة على سمية الکبد والکلى فى الجرذان

Journal of Agricultural Chemistry and Biotechnology
Article 3, Volume 11, Issue 6, June 2020, Page 181-187  XML PDF (764.17 K)
Document Type: Original Article
DOI: 10.21608/jacb.2020.106197
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Authors
Asmaa Kandeel1; A. A. Abd El-Rahman2; R. M. Elsanhoty3; M. A. Al-Saman3; Abdalla El-Hadary email orcid 4
1Biochemistry Department, Faculty of Agriculture, Benha University, Benha 13736, Egypt
2Biochemistry Department, Faculty of Agriculture, Benha University, Benha 13736, Egypt.
3Department of Industrial Biotechnology, Genetic Engineering and Biotechnology Research Institute, University of Sadat City, Sadat City 22857/79, Egypt.
4Biochemistry department,Faculty of agriculture, Benha university
Abstract
This study reports the results of the survey study on 3-monochloro1,2-propanediol (3-MCPD) levels in selected foods, oils and fats collected from supermarkets and restaurants in Egypt. Also; study the effect of feeding of rat on diet contained palm oil rich 3-MCPD on the biochemical parameters of rats. Twenty samples were collected from different supermarkets and restaurants in Egypt to determine 3-MCPD by GC-MS. The oil samples remained after  from falafel  frying showed the highest contents of 3-MCPD esters, with a mean value of 8.20 μg/kg oil, followed by palm oils and oils mixture. Forty Albino rats divided into five groups including one as a basal diet control. The other groups were fed on a a basal diet and replaced corn oil with crude palm oil heated at 200°C for 30min, heated palm oil at 200°C for 6h and palm oil fried with tortilla chips. Rats fed on either heated palm oil at 200°C for 6h and  fried palm oil with tortilla chips showed elevated liver and kidney functions as well as lipid profile except HDL-cholesterol and damages in some histological liver and kidney tissue compared with the control basal diet.This would risk forming esters of 3-MCPD fatty acids. 
Keywords
3-MCPD; frying; palm oil; liver and kidney functions
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