Cytotoxicity of Novel Hydrazide-hydrazone Derivatives towards Tumor and Normal Cell Lines | ||||
Egyptian Journal of Chemistry | ||||
Article 2, Volume 56, Issue 1, February 2013, Page 25-34 PDF (327.85 K) | ||||
DOI: 10.21608/ejchem.2013.1072 | ||||
View on SCiNiTO | ||||
Abstract | ||||
THE REACTION of cyanoacetyl hydrazone with ninhydrin gave …….the hydrazide – hydrazone derivative 3. The reactivity of the later product towards different chemical reagents was studied. The cytotoxicity of the newly synthesized products was measured towards the three cancer cell lines, namely breast adenocarcinoma (MCF-7), non-small cell lung cancer(NCI-H460) and CNS cancer (SF-268). | ||||
Keywords | ||||
Ninhydrin; Hydrazide-hydrazone; Pyridine and Pyridazone | ||||
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