SYNTHESIS AND FUNGICIDAL ACTIVITY OF NEW THIAZOLE DERIVATIVES WERE PREPARED FROM 2-BROMO-1-(3,4-DIMETHYLPHENYL)ETHANONE | ||||
Al-Azhar Bulletin of Science | ||||
Article 11, Volume 19, Issue A-2, December 2008, Page 147-160 PDF (295.07 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/absb.2008.10820 | ||||
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Authors | ||||
MAHMOUD S. BASHANDY* 1; MAHMOUD M. ABDELALL1; AHMED M. EL-MORSY2 | ||||
1Chemistry Department Faculty of Science (Boy's), Al-Azhar University Nasr-City Cairo Egypt | ||||
2Organic Chemistry Department Faculty of pharmacy (Boy's), Al-Azhar University Nasr-City Egypt | ||||
Abstract | ||||
2-bromo-1-(3,4-dimethylphenyl)ethanone (2) was prepared and converted to thiazole derivatives (6-11a-c, 14-20) through reactions with different reagents. Compounds (3, 5, 12, 13, 21) were prepared from reaction of compound (2) with 2-mercapto-4,6-dimethylnicotinonitrile1H-benzo[d]imidazole-2-thiol, p-chloroaniline, potassium cyanide and 2-aminobenzenethiol respectively. The synthesized compounds were confirmed by elemental analysis, IR, 1H-NMR and mass spectral analysis. | ||||
Keywords | ||||
2-bromo-1-phenylethanone; thiazole; 2-aminothiazole; 2-methylthiazole; 2H-chromen-2-one; benzo[b][1,4]thiazine | ||||
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