The Value of Serum Progesterone Level at The Day of Triggering in Prediction of Intracytoplasmic Sperm Injection [ICSI] Outcome
Abo khalil, M., Midan, M., EL-Ghandour, A., Rashed, R. (2020). The Value of Serum Progesterone Level at The Day of Triggering in Prediction of Intracytoplasmic Sperm Injection [ICSI] Outcome. EKB Journal Management System, 2(4), 798-804. doi: 10.21608/ijma.2020.25117.1107
Mohamed Ahmed Abo khalil; Mahmoud Farouk Midan; Abdel Aal Mohamed EL-Ghandour; Rashed Moahmed Rashed. "The Value of Serum Progesterone Level at The Day of Triggering in Prediction of Intracytoplasmic Sperm Injection [ICSI] Outcome". EKB Journal Management System, 2, 4, 2020, 798-804. doi: 10.21608/ijma.2020.25117.1107
Abo khalil, M., Midan, M., EL-Ghandour, A., Rashed, R. (2020). 'The Value of Serum Progesterone Level at The Day of Triggering in Prediction of Intracytoplasmic Sperm Injection [ICSI] Outcome', EKB Journal Management System, 2(4), pp. 798-804. doi: 10.21608/ijma.2020.25117.1107
Abo khalil, M., Midan, M., EL-Ghandour, A., Rashed, R. The Value of Serum Progesterone Level at The Day of Triggering in Prediction of Intracytoplasmic Sperm Injection [ICSI] Outcome. EKB Journal Management System, 2020; 2(4): 798-804. doi: 10.21608/ijma.2020.25117.1107

The Value of Serum Progesterone Level at The Day of Triggering in Prediction of Intracytoplasmic Sperm Injection [ICSI] Outcome

International Journal of Medical Arts
Article 18, Volume 2, Issue 4, October 2020, Page 798-804  XML PDF (2.15 MB)
Document Type: Original Article
DOI: 10.21608/ijma.2020.25117.1107
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Authors
Mohamed Ahmed Abo khalil email orcid 1; Mahmoud Farouk Midan2; Abdel Aal Mohamed EL-Ghandour3; Rashed Moahmed Rashed2
1Department of Obstetrics and Gynecology, El Mahalla General Hospital, Ministry of Health, Egypt
2Department of Obstetrics and Gynecology, Damietta Faculty of Medicine, Al-Azhar University, Egypt
3International Islamic Center for Population Studies and Research, Al-Azhar University, Egypt
Abstract
Background:The potential association of serum progesterone on the day of human chorionic gonadotropin administration with the outcome of intracytoplasmic sperm injection [ICSI] cycles has been one of the major controversies in the endocrinology of ovarian stimulation.
Aim of the work: This study was conducted to estimate the net effect of progesterone elevation on the day of human chorionic gonadotrophin [hCG] on pregnancy outcome in women undergoing fresh embryo transfer in control ovarian stimulation using long agonist and antagonist protocols.
Patients and Methods:This is a prospective study included a total of 177 patients who were indicated for ICSI. The included cases were divided into three groups according to progesterone level at the day of hCG. Both progesterone and E2 were estimated at the day of triggering.
Results:Serum progesterone levels did not differ between cases who got pregnancy and who did not (p=0.435). Estrogen/Progesterone ratio was not significantly different between pregnant and non-pregnant females (p= 0.842).  
Conclusion: Progesterone level on the day of hCG administration does not have any effect on ICSI outcome.
Keywords
Progesterone; ICSI; Estrogen/progesterone ratio; Triggering; Outcome
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