Impact of Opioid Toxicity on Workplace Productivity | ||||
| Egyptian Journal of Occupational Medicine | ||||
| Article 1, Volume 44, Issue 2, April 2020, Page 577-588 PDF (330.59 K) | ||||
| Document Type: Review article | ||||
| DOI: 10.21608/ejom.2020.109572 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
| El Safty AM K; Fouad M M | ||||
| Department of Occupational and Environmental Medicine, Faculty of Medicine, Cairo University, Egypt. | ||||
| Abstract | ||||
| Opioids are derived from opiates they include also synthetic and semi-synthetic drugs. Opioidshave both recreational and medical uses. Opioid abuse is a worldwide problem with numerous andincreasing mortality due to overdose. Opioids act on the opiate receptors as a potent mu receptoragonist resulting in a complex intracellular signals leading to dopamine release causing euphoria,and pain signal blocking. In cases of overdose, there is an excessive effect on respiratory center,resulting in respiratory depression and eventually death. Opioids can lower the perception of painand in some cases decrease the pain stimulus. Stimulation of opiate receptors results in suppressionof pain sensation. Opioids have an extremely wide diversity of durations of action, the intensity and quality of response to opioids can vary significantly between patients. Diagnosis of acute opioid toxicity is mainly clinically and naloxone is the cornerstone of therapy. Opioid addiction traditional treatment includes setting of counseling and mentorship besides drug treatment. Opioid prescription for pain management can have a major impact on future development of opioid use disorder but with careful monitoring and patient education about the potential opioid toxicity and risk of addiction to overcome addiction or overdose development. Opioid addiction has deep impact on workforce productivity in the form of increased absenteeism rate, decreased productive hours and higher rate of work place injuries that lead to economic burden. Our aim is studying the approach for preventing drug abuse and supporting drug users to get their lives back on track and boost workforce productivity. | ||||
| Keywords | ||||
| Opioids; Overdose; Addiction; Opioid prescription and Workplace productivity | ||||
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