Meta-analysis on Corneal Changes following Phacoemulsification in Diabetic vs. Non-diabetic Cataract Patients | ||||
| The Egyptian Journal of Hospital Medicine | ||||
| Article 8, Volume 70, Issue 5, January 2018, Page 754-761 PDF (570.63 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.12816/0043978 | ||||
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| Authors | ||||
| Faisal Ali A Alotaibi1; Rawan Ariman Alosaimi2; Fatimah Hassan Alyahya3; Mohammad Mustafa Alali4; Faris Ali Nasser Ayidh5; Farhan Musafiq Alanazi6; Faisal Fahad Alanizy7; Nora Faisal Alsaud8; Ahmad Sami A Himayda9; Nouf Awad S Albalawi10; Wissam Abdullatif Alsuwailm11; Mohammed Abdullah M Alamri11 | ||||
| 1King Abdulaziz Specialist Hospital | ||||
| 2Jordan university | ||||
| 3King Abdulaziz University | ||||
| 4Imam Abdulrahman Bin Faisal University | ||||
| 5King Khalid University | ||||
| 6Aljouf university | ||||
| 7King Saud Bin Abdulaziz University for Health Sciences | ||||
| 8Alfaisal University | ||||
| 9Umm al-Qura University | ||||
| 10Tabuk University | ||||
| 11King Faisal University | ||||
| Abstract | ||||
| Aim of the Study: was to investigate the influence of phacoemulsification on corneal endothelial cells and its injury risk factors in diabetic cataract patients and non-diabetic patients. Methods: electronic databases were searched: Scopus, EMBASE, and Google Scholer), PubMed/MEDLINE, Scopus, The Cochrane Library, and Web of Science. Econlit from 1990 to 2017. This was completed with a manual search of references of relevant papers. Risk of bias in methodology of studies was measured using the Newcastle-Ottawa Scale. Results: Observation of corneal endothelial cell density, coefficient of variation and percentage of hexagonal cells preoperatively, 1 day, 1week, 1 and 3 months postoperatively was carried out, and multiple Logistic regression analysis for risk factors of corneal endothelial cell injury was taken. Results: Out of 779 retrieved papers, 9 studies with a total of 1129 individuals were finally included (579 diabetic eyes and 550 non-diabetic eyes). For the dynamic changes between preoperative and postoperative values, significant differences were identified between the two groups in endothelial cell density (ECD) and hexagon cells (HC%) at 1 day, 1 week, 1 month, and 3 months postoperatively, in central corneal thickness (CCT) at 1 month postoperatively, and in coefficient variation (CV) at 1 week and 1 month postoperatively. However, no significant differences were observed in CCT at 1 day, 1 week and 3 months postoperatively or in CV at 1 day and 3 months postoperatively. Conclusion: it could be concluded from the current literature that aged-cataract patients with diabetes mellitus manifested poor tolerability to cataract phacoemulsification surgery in contrast to senile cataract patients. | ||||
| Keywords | ||||
| Phacomulsification; Cataract; DM; corneal changes | ||||
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